Interactor 1: HERC2 (O95714)
E3 ubiquitin-protein ligase HERC2 (EC 2.3.2.26) (HECT domain and RCC1-like domain-containing protein 2) (HECT-type E3 ubiquitin transferase HERC2)
Gene: HERC2
Interactor 2: UBE3A (Q05086)
Ubiquitin-protein ligase E3A (EC 2.3.2.26) (E6AP ubiquitin-protein ligase) (HECT-type ubiquitin transferase E3A) (Human papillomavirus E6-associated protein) (Oncogenic protein-associated protein E6-AP) (Renal carcinoma antigen NY-REN-54)
Gene: UBE3A
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.88 | 1.00 | 0.943 |
The method score is based on:
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | HECT~HECT |
| Common GO terms | GO:0005634 - nucleus GO:0005829 - cytosol GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process GO:0061630 - ubiquitin protein ligase activity |
| Homologous interactions | 15 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
