HitPredict

Interactor 1: HERC2 (O95714)
E3 ubiquitin-protein ligase HERC2 (EC 2.3.2.26) (HECT domain and RCC1-like domain-containing protein 2) (HECT-type E3 ubiquitin transferase HERC2)
Gene: HERC2

Interactor 2: NCOA4 (Q13772)
Nuclear receptor coactivator 4 (NCoA-4) (Androgen receptor coactivator 70 kDa protein) (70 kDa AR-activator) (70 kDa androgen receptor coactivator) (Androgen receptor-associated protein of 70 kDa) (Ret-activating protein ELE1)
Gene: NCOA4

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.90	0.60	0.737

Property	Details
Experiments	26436293, 28514442, 37059186, 25476789, 30279242, 29426014
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1 4834 Hs			1 614
+	Hs
		1045302 HUWE1_HUMAN (4365-4788): 5.93e-118: 425: 24.00		NCOA4_HUMAN (1-614): 0: 1241: 100.00
+	Hs
		72788 HUWE1_HUMAN (4365-4788): 5.93e-118: 425: 24.00		B4DF87_HUMAN (124-614): 0: 1000: 100.00