HitPredict

Interactor 1: HERC2 (O95714)
E3 ubiquitin-protein ligase HERC2 (EC 2.3.2.26) (HECT domain and RCC1-like domain-containing protein 2) (HECT-type E3 ubiquitin transferase HERC2)
Gene: HERC2

Interactor 2: RABE1 (Q15276)
Rab GTPase-binding effector protein 1 (Rabaptin-4) (Rabaptin-5) (Rabaptin-5alpha) (Renal carcinoma antigen NY-REN-17)
Gene: RABEP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.50	0.558

Property	Details
Experiments	26186194, 28514442
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 4834 Hs			1 862
+	Hs
		319994 HERC2_HUMAN (1-4834): 0: 6206: 100.00		CP250_HUMAN (203-861): 6.81e-16: 85.1: 10.83
+	Mm
		1118137 HERC2_MOUSE (1-4834): 0: 6208: 95.51		MYH10_MOUSE (486-860): 1.25e-12: 74.3: 11.73
+	Hs
		1070171 SMUF1_HUMAN (4321-4794): 2.56e-156: 507: 20.58		RABE1_HUMAN (1-862): 6.85e-68: 244: 100.00
+	Hs
		125713 WWP2_HUMAN (4317-4794): 2.23e-166: 541: 19.22		RABE2_HUMAN (51-217): 5.05e-20: 96.7: 46.11
+	Hs
		1192196 HUWE1_HUMAN (4365-4788): 5.93e-118: 425: 24.00		CP250_HUMAN (203-861): 6.81e-16: 85.1: 10.83
+	Hs
		724896 HUWE1_HUMAN (4365-4788): 5.93e-118: 425: 24.00		MYH9_HUMAN (486-859): 1.31e-13: 77.4: 12.90
+	Hs
		101702 F8VWT9_HUMAN (4338-4787): 2.28e-33: 145: 28.02		RABE2_HUMAN (51-217): 5.05e-20: 96.7: 46.11
+	Hs
		148866 HERC1_HUMAN (2867-3016): 8.76e-11: 71.4: 12.34		CTRO_HUMAN (31-712): 1.44e-12: 74: 13.86