HitPredict

Interactor 1: HERC2 (O95714)
E3 ubiquitin-protein ligase HERC2 (EC 2.3.2.26) (HECT domain and RCC1-like domain-containing protein 2) (HECT-type E3 ubiquitin transferase HERC2)
Gene: HERC2

Interactor 2: EIF3M (Q7L2H7)
Eukaryotic translation initiation factor 3 subunit M (eIF3m) (Fetal lung protein B5) (hFL-B5) (PCI domain-containing protein 1)
Gene: EIF3M

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.60	0.633

Property	Details
Experiments	25476789, 30279242, 29426014
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 4834 Hs			1 374
+	Hs
		125543 WWP2_HUMAN (4317-4794): 2.23e-166: 541: 19.22		EIF3M_HUMAN (1-374): 7.77e-145: 416: 100.00
+	Hs
		1184121 HUWE1_HUMAN (4365-4788): 5.93e-118: 425: 24.00		EIF3M_HUMAN (1-374): 7.77e-145: 416: 100.00
+	Hs
		1192264 HUWE1_HUMAN (4365-4788): 5.93e-118: 425: 24.00		PSD13_HUMAN (71-369): 5.95e-102: 307: 15.64
+	Hs
		1133264 HECD3_HUMAN (2779-2907): 2.15e-12: 75.9: 36.84		CSN7B_HUMAN (178-370): 7.88e-49: 167: 20.81