HitPredict

Interactor 1: CXL14 (O95715)
C-X-C motif chemokine 14 (Chemokine BRAK) (MIP-2G) (Small-inducible cytokine B14)
Gene: CXCL14

Interactor 2: CCL11 (P51671)
Eotaxin (C-C motif chemokine 11) (Eosinophil chemotactic protein) (Small-inducible cytokine A11)
Gene: CCL11

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.692

Property	Details
Experiments	28381538
Identification Methods	pull down, filter binding
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	IL8~IL8
Common GO terms	GO:0005615 - extracellular space GO:0006935 - chemotaxis GO:0007165 - signal transduction GO:0008009 - chemokine activity
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 111 Hs			1 97
+	Hs
		320109 CXL14_HUMAN (1-111): 2.98e-72: 211: 100.00		CCL13_HUMAN (1-96): 8.14e-35: 116: 64.29
+	Hs
		320085 CXL14_HUMAN (1-111): 2.98e-72: 211: 100.00		CCL5_HUMAN (1-90): 8.3e-25: 90.8: 42.86
+	Hs
		320092 CXL14_HUMAN (1-111): 2.98e-72: 211: 100.00		XCL1_HUMAN (1-95): 1.06e-23: 88.5: 29.47
+	Hs
		320105 CXL14_HUMAN (1-111): 2.98e-72: 211: 100.00		CCL17_HUMAN (6-89): 2.53e-23: 86.9: 32.14
+	Hs
		134280 CXL14_HUMAN (1-111): 2.98e-72: 211: 100.00		CCL21_HUMAN (17-97): 2.54e-22: 85.8: 32.14
+	Hs
		320115 CXL14_HUMAN (1-111): 2.98e-72: 211: 100.00		CCL26_HUMAN (23-93): 1.16e-21: 82.7: 36.62