HitPredict

Interactor 1: CXL14 (O95715)
C-X-C motif chemokine 14 (Chemokine BRAK) (MIP-2G) (Small-inducible cytokine B14)
Gene: CXCL14

Interactor 2: CCL17 (Q92583)
C-C motif chemokine 17 (CC chemokine TARC) (Small-inducible cytokine A17) (Thymus and activation-regulated chemokine)
Gene: CCL17

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	28381538
Identification Methods	surface plasmon resonance
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	IL8~IL8
Common GO terms	GO:0005615 - extracellular space GO:0006935 - chemotaxis GO:0007267 - cell-cell signaling GO:0008009 - chemokine activity
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 111 Hs			1 94
+	Hs
		320109 CXL14_HUMAN (1-111): 2.98e-72: 211: 100.00		CCL13_HUMAN (6-94): 5.69e-34: 113: 29.21
+	Hs
		320095 CXL14_HUMAN (1-111): 2.98e-72: 211: 100.00		CCL11_HUMAN (16-94): 4.16e-27: 96.6: 30.00
+	Hs
		320085 CXL14_HUMAN (1-111): 2.98e-72: 211: 100.00		CCL5_HUMAN (14-90): 3.37e-25: 91.6: 25.97
+	Hs
		320115 CXL14_HUMAN (1-111): 2.98e-72: 211: 100.00		CCL26_HUMAN (22-93): 3.75e-25: 91.6: 27.78
+	Hs
		320092 CXL14_HUMAN (1-111): 2.98e-72: 211: 100.00		XCL1_HUMAN (4-94): 8.75e-23: 86.2: 22.83
+	Hs
		134280 CXL14_HUMAN (1-111): 2.98e-72: 211: 100.00		CCL21_HUMAN (30-93): 4.84e-18: 74.6: 25.00