HitPredict

Interactor 1: ERR2 (O95718)
Steroid hormone receptor ERR2 (ERR beta-2) (Estrogen receptor-like 2) (Estrogen-related receptor beta) (ERR-beta) (Nuclear receptor subfamily 3 group B member 2)
Gene: ESRRB

Interactor 2: 1433T (P27348)
14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1)
Gene: YWHAQ

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	24189400
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 433 Hs			1 245
+	Hs
		369315 ESR1_HUMAN (9-432): 2.54e-114: 349: 32.90		1433E_HUMAN (2-243): 1.31e-144: 406: 63.53
+	Hs
		369023 ESR1_HUMAN (9-432): 2.54e-114: 349: 32.90		1433T_HUMAN (1-245): 9.47e-142: 398: 100.00
+	Hs
		369354 ESR1_HUMAN (9-432): 2.54e-114: 349: 32.90		1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59
+	Hs
		369070 ESR1_HUMAN (9-432): 2.54e-114: 349: 32.90		1433B_HUMAN (1-242): 5.01e-139: 391: 81.82
+	Hs
		909878 ESR2_HUMAN (62-433): 1.47e-105: 324: 35.28		1433E_HUMAN (2-243): 1.31e-144: 406: 63.53
+	Mm
		509305 RARA_MOUSE (39-430): 7.97e-107: 325: 27.25		1433Z_MOUSE (1-245): 3.06e-142: 399: 80.00
+	Hs
		647162 ESR2_HUMAN (62-433): 1.47e-105: 324: 35.28		1433T_HUMAN (1-245): 9.47e-142: 398: 100.00
+	Hs
		927369 ESR2_HUMAN (62-433): 1.47e-105: 324: 35.28		1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59
+	Hs
		683595 ESR2_HUMAN (62-433): 1.47e-105: 324: 35.28		1433B_HUMAN (1-242): 5.01e-139: 391: 81.82
+	Mm
		509343 RARA_MOUSE (39-430): 7.97e-107: 325: 27.25		1433B_MOUSE (1-242): 2.84e-124: 354: 80.99
+	Hs
		369071 ESR1_HUMAN (9-432): 2.54e-114: 349: 32.90		1433S_HUMAN (1-236): 9.86e-108: 312: 71.85
+	Hs
		369308 ESR1_HUMAN (9-432): 2.54e-114: 349: 32.90		1433G_HUMAN (1-242): 5.48e-105: 305: 70.33
+	Hs
		684247 ESR2_HUMAN (62-433): 1.47e-105: 324: 35.28		1433S_HUMAN (1-236): 9.86e-108: 312: 71.85
+	Mm
		509296 RARA_MOUSE (39-430): 7.97e-107: 325: 27.25		1433G_MOUSE (1-242): 5.48e-105: 305: 70.33
+	Hs
		904942 ESR2_HUMAN (62-433): 1.47e-105: 324: 35.28		1433G_HUMAN (1-242): 5.48e-105: 305: 70.33
+	Hs
		377131 GCR_HUMAN (99-352): 3.14e-47: 174: 38.37		1433S_HUMAN (1-236): 9.86e-108: 312: 71.85
+	Hs
		377266 GCR_HUMAN (99-352): 3.14e-47: 174: 38.37		1433F_HUMAN (2-242): 7.16e-106: 307: 71.43