HitPredict

Interactor 1: UFL1 (O94874)
E3 UFM1-protein ligase 1 (EC 2.3.2.-) (E3 UFM1-protein transferase 1) (Multiple alpha-helix protein located at ER) (Novel LZAP-binding protein) (Regulator of C53/LZAP and DDRGK1)
Gene: UFL1

Interactor 2: UFC1 (Q9Y3C8)
Ubiquitin-fold modifier-conjugating enzyme 1 (Ufm1-conjugating enzyme 1)
Gene: UFC1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.82	0.90	0.864

Property	Details
Experiments	32545848, 32807901, 33961781, 37595036
Identification Methods	pull down, affinity chromatography technology, anti tag coimmunoprecipitation, isothermal titration calorimetry
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	E3_UFM1_ligase~UFC1
Common GO terms	GO:0034976 - response to endoplasmic reticulum stress GO:0061709 - reticulophagy GO:0071568 - UFM1 transferase activity GO:0071569 - protein ufmylation GO:1990592 - protein K69-linked ufmylation
Homologous interactions	0