HitPredict

Interactor 1: ERR2 (O95718)
Steroid hormone receptor ERR2 (ERR beta-2) (Estrogen receptor-like 2) (Estrogen-related receptor beta) (ERR-beta) (Nuclear receptor subfamily 3 group B member 2)
Gene: ESRRB

Interactor 2: SPB4 (P48594)
Serpin B4 (Leupin) (Peptidase inhibitor 11) (PI-11) (Squamous cell carcinoma antigen 2) (SCCA-2)
Gene: SERPINB4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 433 Hs			1 390
+	Hs
		369170 ESR1_HUMAN (9-432): 2.54e-114: 349: 32.90		SPB4_HUMAN (1-390): 0: 510: 100.00
+	Hs
		820352 ESR2_HUMAN (62-433): 1.47e-105: 324: 35.28		SPB4_HUMAN (1-390): 0: 510: 100.00
+	Hs
		668005 ESR2_HUMAN (62-433): 1.47e-105: 324: 35.28		SPB3_HUMAN (1-390): 9.6e-176: 496: 91.80
+	Hs
		369104 ESR1_HUMAN (9-432): 2.54e-114: 349: 32.90		SPB5_HUMAN (1-390): 1.15e-135: 394: 33.59
+	Hs
		344173 HNF4A_HUMAN (78-429): 2.14e-110: 335: 27.76		A1AT_HUMAN (2-390): 3.71e-139: 404: 32.82
+	Hs
		344220 ESR2_HUMAN (62-433): 1.47e-105: 324: 35.28		A1AT_HUMAN (2-390): 3.71e-139: 404: 32.82
+	Hs
		377126 GCR_HUMAN (99-352): 3.14e-47: 174: 38.37		ILEU_HUMAN (1-390): 1.86e-151: 434: 46.72
+	Hs
		377147 GCR_HUMAN (99-352): 3.14e-47: 174: 38.37		SPB5_HUMAN (1-390): 1.15e-135: 394: 33.59