Interactor 1: CRTAM (O95727)
Cytotoxic and regulatory T-cell molecule (Class-I MHC-restricted T-cell-associated molecule) (CD antigen CD355)
Gene: CRTAM

Interactor 2: CADM1 (Q9BY67)
Cell adhesion molecule 1 (Immunoglobulin superfamily member 4) (IgSF4) (Nectin-like protein 2) (NECL-2) (Spermatogenic immunoglobulin superfamily) (SgIgSF) (Synaptic cell adhesion molecule) (SynCAM) (Tumor suppressor in lung cancer 1) (TSLC-1)
Gene: CADM1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.53 1.00 0.730

The method score is based on:

Property Details
Experiments 23871486
Identification Methods molecular sieving, x-ray crystallography, surface plasmon resonance, cosedimentation in solution
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains C2-set_2~C2-set_2, C2-set_2~Ig_3, C2-set_2~V-set, Ig_3~V-set, V-set~V-set
Common GO terms GO:0001819 - positive regulation of cytokine production
GO:0005102 - signaling receptor binding
GO:0005886 - plasma membrane
GO:0007157 - heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
GO:0008037 - cell recognition
and 2 others

more...

Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 393
Hs

1 442
+ Dr
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+ Dm
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Last updated: 15 Jul 2024