HitPredict

Interactor 1: OXSR1 (O95747)
Serine/threonine-protein kinase OSR1 (EC 2.7.11.1) (Oxidative stress-responsive 1 protein)
Gene: OXSR1

Interactor 2: RHOB (P62745)
Rho-related GTP-binding protein RhoB (Rho cDNA clone 6) (h6)
Gene: RHOB

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Pkinase~Ras
Common GO terms	GO:0005829 - cytosol GO:0007165 - signal transduction GO:0019901 - protein kinase binding GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 527 Hs			1 196
+	Hs
		320512 OXSR1_HUMAN (1-527): 7e-175: 505: 100.00		RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10
+	Hs
		925702 STK39_HUMAN (10-527): 1.74e-152: 448: 73.75		RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10
+	Hs
		901015 STK39_HUMAN (10-527): 1.74e-152: 448: 73.75		RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67
+	Hs
		647868 MARK3_HUMAN (5-513): 5.55e-130: 397: 19.25		RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10
+	Hs
		647858 MARK3_HUMAN (5-513): 5.55e-130: 397: 19.25		RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67
+	Hs
		647867 MARK3_HUMAN (5-513): 5.55e-130: 397: 19.25		RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00
+	Hs
		545213 MARK3_HUMAN (5-513): 5.55e-130: 397: 19.25		RAC2_HUMAN (1-196): 7.63e-77: 230: 53.57
+	Hs
		900617 MARK2_HUMAN (3-517): 2.86e-128: 394: 18.49		RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67
+	Hs
		436165 MARK3_HUMAN (5-513): 5.55e-130: 397: 19.25		RHOC_HUMAN (1-196): 8.84e-76: 227: 83.16
+	Hs
		545461 MARK2_HUMAN (3-517): 2.86e-128: 394: 18.49		RAC2_HUMAN (1-196): 7.63e-77: 230: 53.57
+	Hs
		647872 MARK3_HUMAN (5-513): 5.55e-130: 397: 19.25		RHOG_HUMAN (1-196): 8.84e-76: 227: 51.53
+	Hs
		436371 MARK2_HUMAN (3-517): 2.86e-128: 394: 18.49		RHOC_HUMAN (1-196): 8.84e-76: 227: 83.16
+	Hs
		647855 MARK3_HUMAN (5-513): 5.55e-130: 397: 19.25		RAC3_HUMAN (1-179): 1.15e-74: 224: 57.54
+	Hs
		647856 MARK3_HUMAN (5-513): 5.55e-130: 397: 19.25		CDC42_HUMAN (1-196): 1.35e-74: 224: 49.49
+	Hs
		892447 MARK2_HUMAN (3-517): 2.86e-128: 394: 18.49		RAC3_HUMAN (1-179): 1.15e-74: 224: 57.54
+	Hs
		894157 MARK2_HUMAN (3-517): 2.86e-128: 394: 18.49		CDC42_HUMAN (1-196): 1.35e-74: 224: 49.49
+	Hs
		564418 MARK3_HUMAN (5-513): 5.55e-130: 397: 19.25		RHOQ_HUMAN (2-195): 6.71e-68: 207: 51.74
+	Hs
		564584 MARK2_HUMAN (3-517): 2.86e-128: 394: 18.49		RHOQ_HUMAN (2-195): 6.71e-68: 207: 51.74
+	Hs
		120307 MARK3_HUMAN (5-513): 5.55e-130: 397: 19.25		RHOD_HUMAN (7-182): 3.37e-66: 203: 53.98
+	Hs
		120505 MARK2_HUMAN (3-517): 2.86e-128: 394: 18.49		RHOD_HUMAN (7-182): 3.37e-66: 203: 53.98