Interactor 1: OXSR1 (O95747)
Serine/threonine-protein kinase OSR1 (EC 2.7.11.1) (Oxidative stress-responsive 1 protein)
Gene: OXSR1

Interactor 2: WNK1 (Q9H4A3)
Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Erythrocyte 65 kDa protein) (p65) (Kinase deficient protein) (Protein kinase lysine-deficient 1) (Protein kinase with no lysine 1) (hWNK1)
Gene: WNK1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.83 1.00 0.913

The method score is based on:

Property Details
Experiments 35271311, 35044719, 16832045, 17721439
Identification Methods affinity chromatography technology, unspecified method, anti bait coimmunoprecipitation, protein kinase assay, two hybrid, phage display, anti tag coimmunoprecipitation, pull down
Interaction Type physical association, direct interaction, phosphorylation reaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains OSR1_C~Pkinase, Pkinase~Pkinase
Common GO terms GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006468 - protein phosphorylation
and 10 others

more...

Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 527
Hs

1 2382
+ Hs
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+ Rn
+ Dm
+ At
+ At
+ At
+ Ce
+ At
+ At
+ Hs
+ Hs
+ At
+ Hs
+ Hs
+ At
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+ Hs
+ Mm

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Last updated: 15 Jul 2024