HitPredict

Interactor 1: HS74L (O95757)
Heat shock 70 kDa protein 4L (Heat shock 70-related protein APG-1) (Heat shock protein family H member 3) (Heat-shock protein family A member 4-like protein) (HSPA4-like protein) (Osmotic stress protein 94)
Gene: HSPA4L

Interactor 2: DNJB2 (P25686)
DnaJ homolog subfamily B member 2 (Heat shock 40 kDa protein 3) (Heat shock protein J1) (HSJ-1)
Gene: DNAJB2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	33957083
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	DnaJ~HSP70
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0006986 - response to unfolded protein
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 839 Hs			1 324
+	Hs
		636462 HSP74_HUMAN (1-839): 0: 931: 62.60		DNJB2_HUMAN (1-324): 1.9e-125: 363: 100.00
+	Hs
		320814 HS74L_HUMAN (1-839): 0: 1032: 100.00		DNJB1_HUMAN (2-161): 3.26e-43: 153: 40.63
+	Hs
		258129 HS105_HUMAN (1-839): 0: 925: 58.24		DNJB6_HUMAN (1-283): 7.47e-82: 252: 47.63
+	Hs
		714317 HSP74_HUMAN (1-839): 0: 931: 62.60		DNJB8_HUMAN (1-208): 1.52e-66: 210: 47.79
+	Hs
		279281 HSP74_HUMAN (1-839): 0: 931: 62.60		DNJB5_HUMAN (2-239): 5.52e-44: 155: 25.88
+	Hs
		714449 HSP74_HUMAN (1-839): 0: 931: 62.60		DNJB4_HUMAN (2-238): 5.01e-44: 155: 28.98
+	Hs
		636257 HSP74_HUMAN (1-839): 0: 931: 62.60		DNJB1_HUMAN (2-161): 3.26e-43: 153: 40.63
+	Hs
		714326 HSP74_HUMAN (1-839): 0: 931: 62.60		DNJB3_HUMAN (1-131): 1.76e-44: 150: 53.44
+	Hs
		1267773 HS105_HUMAN (1-839): 0: 925: 58.24		DNJB4_HUMAN (2-238): 5.01e-44: 155: 28.98
+	Hs
		279330 HS105_HUMAN (1-839): 0: 925: 58.24		DNJB5_HUMAN (2-239): 5.52e-44: 155: 25.88
+	Hs
		636386 HS105_HUMAN (1-839): 0: 925: 58.24		DNJB1_HUMAN (2-161): 3.26e-43: 153: 40.63
+	Hs
		1123860 HS105_HUMAN (1-839): 0: 925: 58.24		Q59E89_HUMAN (2-238): 1.02e-42: 152: 28.98
+	Hs
		714320 HSP74_HUMAN (1-839): 0: 931: 62.60		DJB14_HUMAN (2-150): 3.25e-40: 146: 34.67
+	Dm
		1096122 Q9VUC1_DROME (1-837): 0: 855: 42.71		DNAJ1_DROME (2-242): 1.7e-45: 159: 28.86
+	Ce
		450534 HSP1_CAEEL (2-603): 0: 808: 28.78		Q20774_CAEEL (2-263): 8.25e-50: 170: 26.57
+	Hs
		636461 HS71L_HUMAN (563-703): 9.9e-28: 121: 19.72		DNJB2_HUMAN (1-324): 1.9e-125: 363: 100.00
+	Hs
		257928 HS71L_HUMAN (563-703): 9.9e-28: 121: 19.72		DNJB6_HUMAN (1-283): 7.47e-82: 252: 47.63
+	Hs
		714022 HS71L_HUMAN (563-703): 9.9e-28: 121: 19.72		DNJB8_HUMAN (1-208): 1.52e-66: 210: 47.79
+	Hs
		279280 HS71L_HUMAN (563-703): 9.9e-28: 121: 19.72		DNJB5_HUMAN (2-239): 5.52e-44: 155: 25.88
+	Hs
		636256 HS71L_HUMAN (563-703): 9.9e-28: 121: 19.72		DNJB1_HUMAN (2-161): 3.26e-43: 153: 40.63