HitPredict

Interactor 1: PTBP3 (O95758)
Polypyrimidine tract-binding protein 3 (Regulator of differentiation 1) (Rod1)
Gene: PTBP3

Interactor 2: BMI1 (P35226)
Polycomb complex protein BMI-1 (Polycomb group RING finger protein 4) (RING finger protein 51)
Gene: BMI1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	24457600, 34316702
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 552 Hs			1 326
+	Hs
		643431 PTBP1_HUMAN (1-552): 1.59e-114: 352: 75.27		BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00
+	Hs
		718289 PTBP2_HUMAN (1-552): 3.79e-96: 304: 66.00		BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00
+	Hs
		540907 HNRPL_HUMAN (47-551): 6.01e-60: 210: 24.24		BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00
+	Hs
		717783 PABP4_HUMAN (4-266): 3.85e-37: 147: 13.55		BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00
+	Hs
		516378 PABP1_HUMAN (4-266): 3.64e-36: 144: 12.45		BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00
+	Hs
		718193 PABP3_HUMAN (4-273): 3.75e-34: 138: 11.43		BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00
+	Hs
		320975 PTBP3_HUMAN (1-552): 2.33e-115: 354: 100.00		RO52_HUMAN (5-198): 5.75e-52: 180: 18.78
+	Hs
		643575 PTBP1_HUMAN (1-552): 1.59e-114: 352: 75.27		RING2_HUMAN (7-227): 8.37e-50: 170: 16.61
+	Hs
		717893 PAP1L_HUMAN (472-549): 1.4e-13: 75.4: 20.73		BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00
+	Hs
		541120 HNRPL_HUMAN (47-551): 6.01e-60: 210: 24.24		RING2_HUMAN (7-227): 8.37e-50: 170: 16.61
+	Hs
		1031435 PABP4_HUMAN (4-266): 3.85e-37: 147: 13.55		RING2_HUMAN (7-227): 8.37e-50: 170: 16.61
+	Hs
		282502 PABP1_HUMAN (4-266): 3.64e-36: 144: 12.45		RNF8_HUMAN (2-101): 3.38e-21: 95.7: 25.00