HitPredict

Interactor 1: PTBP3 (O95758)
Polypyrimidine tract-binding protein 3 (Regulator of differentiation 1) (Rod1)
Gene: PTBP3

Interactor 2: IF4A3 (P38919)
Eukaryotic initiation factor 4A-III (eIF-4A-III) (eIF4A-III) (EC 3.6.4.13) (ATP-dependent RNA helicase DDX48) (ATP-dependent RNA helicase eIF4A-3) (DEAD box protein 48) (Eukaryotic initiation factor 4A-like NUK-34) (Eukaryotic translation initiation factor 4A isoform 3) (Nuclear matrix protein 265) (NMP 265) (hNMP 265) [Cleaved into: Eukaryotic initiation factor 4A-III, N-terminally processed]
Gene: EIF4A3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29395067
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0003729 - mRNA binding GO:0005634 - nucleus
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 552 Hs			1 411
+	Hs
		892791 PABP4_HUMAN (4-266): 3.85e-37: 147: 13.55		IF4A1_HUMAN (7-411): 1.67e-178: 505: 66.75
+	Hs
		516434 PABP1_HUMAN (4-266): 3.64e-36: 144: 12.45		IF4A1_HUMAN (7-411): 1.67e-178: 505: 66.75
+	Hs
		1031325 PABP4_HUMAN (4-266): 3.85e-37: 147: 13.55		IF4A2_HUMAN (20-411): 4.07e-177: 501: 69.47
+	Hs
		516515 PABP1_HUMAN (4-266): 3.64e-36: 144: 12.45		IF4A2_HUMAN (20-411): 4.07e-177: 501: 69.47
+	Hs
		540915 HNRPL_HUMAN (47-551): 6.01e-60: 210: 24.24		IF4A3_HUMAN (1-411): 1.22e-142: 414: 100.00
+	Hs
		540891 HNRPL_HUMAN (47-551): 6.01e-60: 210: 24.24		DDX5_HUMAN (25-411): 6.87e-135: 401: 30.63
+	Hs
		541086 HNRPL_HUMAN (47-551): 6.01e-60: 210: 24.24		DDX17_HUMAN (14-411): 1.24e-132: 399: 30.79
+	Hs
		516391 PABP1_HUMAN (4-266): 3.64e-36: 144: 12.45		IF4A3_HUMAN (1-411): 1.22e-142: 414: 100.00
+	Hs
		134018 PABP4_HUMAN (4-266): 3.85e-37: 147: 13.55		DDX3X_HUMAN (17-410): 2.28e-129: 388: 32.45
+	Hs
		133858 PABP1_HUMAN (4-266): 3.64e-36: 144: 12.45		DDX3X_HUMAN (17-410): 2.28e-129: 388: 32.45
+	Hs
		757647 RBM20_HUMAN (59-183): 1.65e-23: 107: 34.92		IF4A3_HUMAN (1-411): 1.22e-142: 414: 100.00
+	Zm
		20968 C0PM53_MAIZE (164-431): 1.93e-16: 81: 24.10		A0A1D6HQ89_MAIZE (2-411): 5.21e-152: 438: 70.63
+	Hs
		640464 PABP4_HUMAN (4-266): 3.85e-37: 147: 13.55		DDX6_HUMAN (35-407): 1.15e-88: 278: 37.83
+	Hs
		516363 PABP1_HUMAN (4-266): 3.64e-36: 144: 12.45		DDX6_HUMAN (35-407): 1.15e-88: 278: 37.83
+	Hs
		640620 PABP3_HUMAN (4-273): 3.75e-34: 138: 11.43		DDX6_HUMAN (35-407): 1.15e-88: 278: 37.83