HitPredict

Interactor 1: PTBP3 (O95758)
Polypyrimidine tract-binding protein 3 (Regulator of differentiation 1) (Rod1)
Gene: PTBP3

Interactor 2: ELAV2 (Q12926)
ELAV-like protein 2 (ELAV-like neuronal protein 1) (Hu-antigen B) (HuB) (Nervous system-specific RNA-binding protein Hel-N1)
Gene: ELAVL2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	RRM_1~RRM_5
Common GO terms	GO:0003723 - RNA binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 552 Hs			1 359
+	Hs
		540986 HNRPL_HUMAN (47-551): 6.01e-60: 210: 24.24		ELAV2_HUMAN (1-359): 5.95e-103: 309: 100.00
+	Dm
		114292 ELAV_DROME (29-434): 1.4e-56: 198: 20.53		M9PBZ2_DROME (34-358): 2.38e-83: 268: 59.88
+	Hs
		320984 PTBP3_HUMAN (1-552): 2.33e-115: 354: 100.00		RBMS1_HUMAN (37-227): 8.76e-27: 111: 36.55
+	Dm
		284190 Q7KRS7_DROME (7-552): 1.61e-87: 284: 47.45		O76876_DROME (37-218): 3.39e-49: 173: 47.80
+	Dm
		284196 Q8WR53_DROME (7-552): 1.36e-87: 284: 47.45		O76876_DROME (37-218): 3.39e-49: 173: 47.80
+	Hs
		1020249 PABP4_HUMAN (4-266): 3.85e-37: 147: 13.55		ELAV2_HUMAN (1-359): 5.95e-103: 309: 100.00
+	Hs
		321088 PTBP3_HUMAN (1-552): 2.33e-115: 354: 100.00		ELAV1_HUMAN (24-120): 1.32e-17: 84.3: 29.90
+	Dm
		562814 ELAV_DROME (29-434): 1.4e-56: 198: 20.53		ELAV_DROME (17-357): 9.08e-75: 240: 50.14
+	Hs
		643518 PTBP1_HUMAN (1-552): 1.59e-114: 352: 75.27		ELAV1_HUMAN (24-120): 1.32e-17: 84.3: 29.90
+	Hs
		1077531 PTBP2_HUMAN (1-552): 3.79e-96: 304: 66.00		ELAV1_HUMAN (24-120): 1.32e-17: 84.3: 29.90
+	Hs
		1073908 RBM19_HUMAN (44-549): 3.53e-79: 269: 17.64		RBMS2_HUMAN (32-217): 2.99e-25: 107: 36.27
+	Hs
		516346 HNRPL_HUMAN (47-551): 6.01e-60: 210: 24.24		PABP1_HUMAN (115-358): 1.39e-44: 164: 20.88
+	Hs
		541018 HNRPL_HUMAN (47-551): 6.01e-60: 210: 24.24		RBMS2_HUMAN (32-217): 2.99e-25: 107: 36.27
+	Hs
		516495 PABP4_HUMAN (4-266): 3.85e-37: 147: 13.55		PABP1_HUMAN (115-358): 1.39e-44: 164: 20.88
+	Hs
		516339 PABP1_HUMAN (4-266): 3.64e-36: 144: 12.45		PABP1_HUMAN (115-358): 1.39e-44: 164: 20.88
+	Hs
		541020 HNRPL_HUMAN (47-551): 6.01e-60: 210: 24.24		ELAV1_HUMAN (24-120): 1.32e-17: 84.3: 29.90
+	Dm
		562818 ELAV_DROME (29-434): 1.4e-56: 198: 20.53		Q9VYI0_DROME (251-357): 1.63e-17: 84.3: 20.00
+	Hs
		668348 PABP4_HUMAN (4-266): 3.85e-37: 147: 13.55		RBMS1_HUMAN (37-227): 8.76e-27: 111: 36.55
+	Hs
		516371 PABP1_HUMAN (4-266): 3.64e-36: 144: 12.45		RBMS1_HUMAN (37-227): 8.76e-27: 111: 36.55
+	Hs
		1031344 PABP4_HUMAN (4-266): 3.85e-37: 147: 13.55		ELAV1_HUMAN (24-120): 1.32e-17: 84.3: 29.90