HitPredict

Interactor 1: PTBP3 (O95758)
Polypyrimidine tract-binding protein 3 (Regulator of differentiation 1) (Rod1)
Gene: PTBP3

Interactor 2: TADBP (Q13148)
TAR DNA-binding protein 43 (TDP-43)
Gene: TARDBP

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	22575643
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	RRM_1~RRM_5
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0006397 - mRNA processing GO:0008380 - RNA splicing
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 552 Hs			1 414
+	Hs
		643489 PTBP1_HUMAN (1-552): 1.59e-114: 352: 75.27		TADBP_HUMAN (1-414): 4.24e-84: 264: 100.00
+	Hs
		320990 PTBP3_HUMAN (1-552): 2.33e-115: 354: 100.00		TIA1_HUMAN (99-413): 2.4e-38: 144: 13.76
+	Hs
		540990 HNRPL_HUMAN (47-551): 6.01e-60: 210: 24.24		TADBP_HUMAN (1-414): 4.24e-84: 264: 100.00
+	Hs
		643501 PTBP1_HUMAN (1-552): 1.59e-114: 352: 75.27		HNRPD_HUMAN (81-238): 5.59e-21: 95.1: 35.93
+	Hs
		161953 HNRPL_HUMAN (47-551): 6.01e-60: 210: 24.24		HNRDL_HUMAN (62-376): 5.62e-71: 231: 23.60
+	Hs
		540936 HNRPL_HUMAN (47-551): 6.01e-60: 210: 24.24		ROA3_HUMAN (98-269): 2.33e-69: 225: 28.57
+	Hs
		1025728 PABP4_HUMAN (4-266): 3.85e-37: 147: 13.55		TADBP_HUMAN (1-414): 4.24e-84: 264: 100.00
+	Hs
		516491 PABP1_HUMAN (4-266): 3.64e-36: 144: 12.45		TADBP_HUMAN (1-414): 4.24e-84: 264: 100.00
+	Hs
		1048269 PTBP2_HUMAN (1-552): 3.79e-96: 304: 66.00		HNRPD_HUMAN (81-238): 5.59e-21: 95.1: 35.93
+	Hs
		162035 PABP4_HUMAN (4-266): 3.85e-37: 147: 13.55		HNRDL_HUMAN (62-376): 5.62e-71: 231: 23.60
+	Hs
		161948 PABP1_HUMAN (4-266): 3.64e-36: 144: 12.45		HNRDL_HUMAN (62-376): 5.62e-71: 231: 23.60
+	Hs
		516424 PABP1_HUMAN (4-266): 3.64e-36: 144: 12.45		ROA3_HUMAN (98-269): 2.33e-69: 225: 28.57
+	Hs
		474021 PABP4_HUMAN (4-266): 3.85e-37: 147: 13.55		PAB4L_HUMAN (2-276): 8.18e-56: 189: 16.96
+	Hs
		516346 HNRPL_HUMAN (47-551): 6.01e-60: 210: 24.24		PABP1_HUMAN (2-382): 7.78e-31: 126: 15.95
+	Hs
		541005 HNRPL_HUMAN (47-551): 6.01e-60: 210: 24.24		HNRPD_HUMAN (81-238): 5.59e-21: 95.1: 35.93
+	Dm
		562815 ELAV_DROME (29-434): 1.4e-56: 198: 20.53		Q8IMS8_DROME (106-263): 7.44e-21: 96.7: 35.76
+	Dm
		562817 ELAV_DROME (29-434): 1.4e-56: 198: 20.53		Q9VBQ1_DROME (106-263): 1.15e-20: 96.3: 35.76
+	Mm
		665745 PABP1_MOUSE (4-266): 2.93e-36: 145: 12.45		TIA1_MOUSE (99-413): 1.08e-36: 139: 12.92
+	Hs
		516495 PABP4_HUMAN (4-266): 3.85e-37: 147: 13.55		PABP1_HUMAN (2-382): 7.78e-31: 126: 15.95
+	Hs
		516339 PABP1_HUMAN (4-266): 3.64e-36: 144: 12.45		PABP1_HUMAN (2-382): 7.78e-31: 126: 15.95