HitPredict

Interactor 1: PTBP3 (O95758)
Polypyrimidine tract-binding protein 3 (Regulator of differentiation 1) (Rod1)
Gene: PTBP3

Interactor 2: ELAV1 (Q15717)
ELAV-like protein 1 (Hu-antigen R) (HuR)
Gene: ELAVL1

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	1.00	0.737

Property	Details
Experiments	29395067, 22575643
Identification Methods	proximity labelling technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	RRM_1~RRM_5
Common GO terms	GO:0003723 - RNA binding GO:0003729 - mRNA binding GO:0005634 - nucleus
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 552 Hs			1 326
+	Hs
		643518 PTBP1_HUMAN (1-552): 1.59e-114: 352: 75.27		ELAV1_HUMAN (1-326): 8.27e-90: 273: 100.00
+	Hs
		1077531 PTBP2_HUMAN (1-552): 3.79e-96: 304: 66.00		ELAV1_HUMAN (1-326): 8.27e-90: 273: 100.00
+	Hs
		541020 HNRPL_HUMAN (47-551): 6.01e-60: 210: 24.24		ELAV1_HUMAN (1-326): 8.27e-90: 273: 100.00
+	Dm
		114292 ELAV_DROME (29-434): 1.4e-56: 198: 20.53		M9PBZ2_DROME (15-326): 4.1e-81: 261: 52.99
+	Dm
		284190 Q7KRS7_DROME (7-552): 1.61e-87: 284: 47.45		O76876_DROME (20-199): 1.12e-47: 168: 46.11
+	Dm
		284196 Q8WR53_DROME (7-552): 1.36e-87: 284: 47.45		O76876_DROME (20-199): 1.12e-47: 168: 46.11
+	Hs
		321063 PTBP3_HUMAN (1-552): 2.33e-115: 354: 100.00		ELAV2_HUMAN (212-322): 4.72e-22: 97: 25.23
+	Dm
		562818 ELAV_DROME (29-434): 1.4e-56: 198: 20.53		Q9VYI0_DROME (3-325): 4.64e-77: 241: 51.16
+	Dm
		562814 ELAV_DROME (29-434): 1.4e-56: 198: 20.53		ELAV_DROME (2-325): 2.03e-72: 233: 45.61
+	Hs
		1031344 PABP4_HUMAN (4-266): 3.85e-37: 147: 13.55		ELAV1_HUMAN (1-326): 8.27e-90: 273: 100.00
+	Hs
		540986 HNRPL_HUMAN (47-551): 6.01e-60: 210: 24.24		ELAV2_HUMAN (212-322): 4.72e-22: 97: 25.23
+	Hs
		516346 HNRPL_HUMAN (47-551): 6.01e-60: 210: 24.24		PABP1_HUMAN (234-325): 2.15e-20: 93.5: 19.57
+	Hs
		1020249 PABP4_HUMAN (4-266): 3.85e-37: 147: 13.55		ELAV2_HUMAN (212-322): 4.72e-22: 97: 25.23
+	Hs
		516484 PABP1_HUMAN (4-266): 3.64e-36: 144: 12.45		ELAV2_HUMAN (212-322): 4.72e-22: 97: 25.23
+	Hs
		516495 PABP4_HUMAN (4-266): 3.85e-37: 147: 13.55		PABP1_HUMAN (234-325): 2.15e-20: 93.5: 19.57
+	Hs
		516339 PABP1_HUMAN (4-266): 3.64e-36: 144: 12.45		PABP1_HUMAN (234-325): 2.15e-20: 93.5: 19.57
+	Hs
		516689 PABP1_HUMAN (4-266): 3.64e-36: 144: 12.45		PABP3_HUMAN (234-325): 3.78e-18: 87: 17.39
+	Hs
		474021 PABP4_HUMAN (4-266): 3.85e-37: 147: 13.55		PAB4L_HUMAN (20-184): 3.03e-12: 68.6: 28.42