HitPredict

Interactor 1: PTBP3 (O95758)
Polypyrimidine tract-binding protein 3 (Regulator of differentiation 1) (Rod1)
Gene: PTBP3

Interactor 2: U1SBP (Q16560)
U11/U12 small nuclear ribonucleoprotein 35 kDa protein (U11/U12 snRNP 35 kDa protein) (U11/U12-35K) (Protein HM-1) (U1 snRNP-binding protein homolog)
Gene: SNRNP35

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	22575643
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	RRM_1~RRM_5
Common GO terms	GO:0003729 - mRNA binding GO:0005634 - nucleus GO:0008380 - RNA splicing
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 552 Hs			1 246
+	Hs
		441891 PTBP1_HUMAN (1-552): 1.59e-114: 352: 75.27		RU17_HUMAN (36-135): 1.04e-38: 141: 45.10
+	Hs
		320990 PTBP3_HUMAN (1-552): 2.33e-115: 354: 100.00		TIA1_HUMAN (19-220): 1.23e-21: 94: 10.90
+	Hs
		321063 PTBP3_HUMAN (1-552): 2.33e-115: 354: 100.00		ELAV2_HUMAN (42-131): 3.68e-15: 75.6: 31.11
+	Hs
		441859 HNRPL_HUMAN (47-551): 6.01e-60: 210: 24.24		RU17_HUMAN (36-135): 1.04e-38: 141: 45.10
+	Hs
		442340 HNRLL_HUMAN (18-551): 4.91e-60: 209: 22.69		RU17_HUMAN (36-135): 1.04e-38: 141: 45.10
+	Hs
		516346 HNRPL_HUMAN (47-551): 6.01e-60: 210: 24.24		PABP1_HUMAN (4-229): 4.07e-25: 105: 13.58
+	Hs
		442125 PABP4_HUMAN (4-266): 3.85e-37: 147: 13.55		RU17_HUMAN (36-135): 1.04e-38: 141: 45.10
+	Hs
		540986 HNRPL_HUMAN (47-551): 6.01e-60: 210: 24.24		ELAV2_HUMAN (42-131): 3.68e-15: 75.6: 31.11
+	Hs
		441852 PABP1_HUMAN (4-266): 3.64e-36: 144: 12.45		RU17_HUMAN (36-135): 1.04e-38: 141: 45.10
+	Dm
		114292 ELAV_DROME (29-434): 1.4e-56: 198: 20.53		M9PBZ2_DROME (48-131): 8.76e-16: 78.3: 29.76
+	Hs
		516495 PABP4_HUMAN (4-266): 3.85e-37: 147: 13.55		PABP1_HUMAN (4-229): 4.07e-25: 105: 13.58
+	Hs
		516339 PABP1_HUMAN (4-266): 3.64e-36: 144: 12.45		PABP1_HUMAN (4-229): 4.07e-25: 105: 13.58
+	Hs
		474021 PABP4_HUMAN (4-266): 3.85e-37: 147: 13.55		PAB4L_HUMAN (52-234): 1.72e-24: 101: 18.58
+	Hs
		516689 PABP1_HUMAN (4-266): 3.64e-36: 144: 12.45		PABP3_HUMAN (42-232): 1.4e-22: 97.9: 16.75
+	Mm
		665745 PABP1_MOUSE (4-266): 2.93e-36: 145: 12.45		TIA1_MOUSE (19-227): 8.45e-21: 91.7: 10.05
+	Hs
		516471 PABP1_HUMAN (4-266): 3.64e-36: 144: 12.45		TIAR_HUMAN (19-196): 3.29e-19: 87.1: 11.73
+	Hs
		1020249 PABP4_HUMAN (4-266): 3.85e-37: 147: 13.55		ELAV2_HUMAN (42-131): 3.68e-15: 75.6: 31.11
+	Hs
		516484 PABP1_HUMAN (4-266): 3.64e-36: 144: 12.45		ELAV2_HUMAN (42-131): 3.68e-15: 75.6: 31.11