HitPredict

Interactor 1: PTBP3 (O95758)
Polypyrimidine tract-binding protein 3 (Regulator of differentiation 1) (Rod1)
Gene: PTBP3

Interactor 2: MKRN2 (Q9H000)
E3 ubiquitin-protein ligase makorin-2 (EC 2.3.2.27) (RING finger protein 62) (RING-type E3 ubiquitin transferase makorin-2)
Gene: MKRN2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 552 Hs			1 416
+	Hs
		1031454 PABP4_HUMAN (4-266): 3.85e-37: 147: 13.55		MKRN2_HUMAN (1-416): 5.68e-170: 484: 100.00
+	Hs
		516684 PABP1_HUMAN (4-266): 3.64e-36: 144: 12.45		MKRN2_HUMAN (1-416): 5.68e-170: 484: 100.00
+	Hs
		1031488 PABP4_HUMAN (4-266): 3.85e-37: 147: 13.55		MKRN1_HUMAN (3-398): 4.09e-149: 433: 45.71
+	Hs
		516728 PABP1_HUMAN (4-266): 3.64e-36: 144: 12.45		MKRN1_HUMAN (3-398): 4.09e-149: 433: 45.71
+	Hs
		1023456 PABP4_HUMAN (4-266): 3.85e-37: 147: 13.55		MKRN3_HUMAN (3-351): 8.84e-109: 331: 39.77
+	Hs
		516487 PABP1_HUMAN (4-266): 3.64e-36: 144: 12.45		MKRN3_HUMAN (3-351): 8.84e-109: 331: 39.77
+	Hs
		1023561 PABP3_HUMAN (4-273): 3.75e-34: 138: 11.43		MKRN3_HUMAN (3-351): 8.84e-109: 331: 39.77
+	Hs
		643548 PTBP1_HUMAN (1-552): 1.59e-114: 352: 75.27		ZC3H8_HUMAN (7-55): 1.25e-13: 73: 42.86
+	Hs
		1139674 HNRLL_HUMAN (18-551): 4.91e-60: 209: 22.69		MBNL2_HUMAN (7-224): 1.03e-35: 136: 13.10
+	Hs
		1221513 RBM19_HUMAN (44-549): 3.53e-79: 269: 17.64		ZC3H3_HUMAN (4-140): 1.11e-10: 65.6: 25.18
+	Hs
		541195 HNRPL_HUMAN (47-551): 6.01e-60: 210: 24.24		ZC3H4_HUMAN (5-55): 8.4e-15: 78.7: 41.18
+	Hs
		541171 HNRPL_HUMAN (47-551): 6.01e-60: 210: 24.24		MBNL1_HUMAN (1-168): 5.44e-09: 59.6: 13.79
+	Hs
		1031384 PABP4_HUMAN (4-266): 3.85e-37: 147: 13.55		ZC3H3_HUMAN (4-140): 1.11e-10: 65.6: 25.18
+	Hs
		1221460 PABP3_HUMAN (4-273): 3.75e-34: 138: 11.43		ZC3H3_HUMAN (4-140): 1.11e-10: 65.6: 25.18