HitPredict

Interactor 1: WIZ (O95785)
Protein Wiz (Widely-interspaced zinc finger-containing protein) (Zinc finger protein 803)
Gene: WIZ

Interactor 2: CBX5 (P45973)
Chromobox protein homolog 5 (Antigen p25) (Heterochromatin protein 1 homolog alpha) (HP1 alpha)
Gene: CBX5

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	24981860, 20562864
Identification Methods	affinity chromatography technology, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0044877 - protein-containing complex binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1651 Hs			1 191
+	Hs
		321765 WIZ_HUMAN (1-1638): 0: 1453: 100.00		CBX3_HUMAN (1-181): 3.06e-62: 192: 60.22
+	Hs
		321752 WIZ_HUMAN (1-1638): 0: 1453: 100.00		CBX1_HUMAN (26-180): 2.32e-55: 175: 60.65
+	Mm
		291345 WIZ_MOUSE (1-1651): 0: 1419: 80.86		Q9DCC5_MOUSE (1-181): 3.06e-62: 192: 60.22
+	Hs
		203610 WIZ_HUMAN (1-1638): 0: 1453: 100.00		SUV91_HUMAN (4-135): 2.04e-36: 132: 19.70
+	Hs
		321854 WIZ_HUMAN (1-1638): 0: 1453: 100.00		CDYL_HUMAN (6-159): 1.34e-34: 129: 22.84
+	Hs
		321834 WIZ_HUMAN (1-1638): 0: 1453: 100.00		SUV92_HUMAN (3-134): 5.96e-33: 123: 24.64
+	Hs
		321802 WIZ_HUMAN (1-1638): 0: 1453: 100.00		CDYL2_HUMAN (18-134): 2.57e-27: 109: 26.83
+	Hs
		123155 WIZ_HUMAN (1-1638): 0: 1453: 100.00		CBX4_HUMAN (11-125): 7.54e-26: 105: 25.22
+	Hs
		321860 WIZ_HUMAN (1-1638): 0: 1453: 100.00		CDY2_HUMAN (17-160): 5.79e-26: 105: 20.67
+	Hs
		64135 ZN729_HUMAN (464-1285): 1.44e-133: 449: 11.92		CBX5_HUMAN (1-191): 1.24e-68: 209: 100.00
+	Hs
		67424 ZN850_HUMAN (480-1419): 1.32e-137: 456: 13.42		CBX3_HUMAN (1-181): 3.06e-62: 192: 60.22
+	Hs
		64140 ZN729_HUMAN (464-1285): 1.44e-133: 449: 11.92		CBX3_HUMAN (1-181): 3.06e-62: 192: 60.22
+	Hs
		64138 ZN729_HUMAN (464-1285): 1.44e-133: 449: 11.92		CBX1_HUMAN (26-180): 2.32e-55: 175: 60.65
+	Hs
		983755 ZNF91_HUMAN (569-1285): 1.72e-106: 371: 13.03		CBX3_HUMAN (1-181): 3.06e-62: 192: 60.22
+	Hs
		316190 ZN624_HUMAN (624-1277): 8.69e-120: 401: 12.81		CBX6_HUMAN (11-103): 2.2e-24: 100: 31.18
+	Hs
		800406 Z585B_HUMAN (717-1419): 4.39e-69: 251: 12.29		CBX5_HUMAN (1-191): 1.24e-68: 209: 100.00
+	Hs
		800425 Z585A_HUMAN (735-1419): 4.23e-69: 251: 12.93		CBX5_HUMAN (1-191): 1.24e-68: 209: 100.00
+	Hs
		1316054 ZN717_HUMAN (586-1285): 1.42e-96: 336: 10.48		CBX8_HUMAN (11-132): 1.8e-29: 113: 25.41
+	Hs
		87558 C9JVC3_HUMAN (586-1285): 8.88e-95: 329: 10.48		CBX8_HUMAN (11-132): 1.8e-29: 113: 25.41
+	Hs
		316196 ZN107_HUMAN (720-1285): 1.07e-64: 238: 11.26		CBX6_HUMAN (11-103): 2.2e-24: 100: 31.18