HitPredict

Interactor 1: WIZ (O95785)
Protein Wiz (Widely-interspaced zinc finger-containing protein) (Zinc finger protein 803)
Gene: WIZ

Interactor 2: SOX2 (P48431)
Transcription factor SOX-2
Gene: SOX2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	28794006, 35140242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 1651 Hs			1 317
+	Hs
		321836 WIZ_HUMAN (1-1638): 0: 1453: 100.00		SOX17_HUMAN (7-260): 1.35e-34: 132: 28.19
+	Hs
		321816 WIZ_HUMAN (1-1638): 0: 1453: 100.00		CIC_HUMAN (3-272): 8.9e-33: 130: 22.26
+	Hs
		321823 WIZ_HUMAN (1-1638): 0: 1453: 100.00		SOX7_HUMAN (23-299): 8.76e-34: 129: 27.03
+	Hs
		225699 WIZ_HUMAN (1-1638): 0: 1453: 100.00		SOX15_HUMAN (13-118): 1.78e-31: 119: 66.04
+	Hs
		996776 ZFP62_HUMAN (561-1419): 7.08e-88: 310: 13.75		SSRP1_HUMAN (24-203): 1.77e-31: 125: 15.68
+	Hs
		818465 ZN644_HUMAN (696-815): 5.16e-44: 178: 40.95		SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00
+	Hs
		996971 ZN257_HUMAN (299-489): 6.08e-50: 189: 15.92		SSRP1_HUMAN (24-203): 1.77e-31: 125: 15.68
+	Hs
		1331883 ZN644_HUMAN (696-815): 5.16e-44: 178: 40.95		SOX17_HUMAN (7-260): 1.35e-34: 132: 28.19
+	Hs
		996898 ZN644_HUMAN (696-815): 5.16e-44: 178: 40.95		SSRP1_HUMAN (24-203): 1.77e-31: 125: 15.68
+	Hs
		225787 ZN644_HUMAN (696-815): 5.16e-44: 178: 40.95		SOX15_HUMAN (13-118): 1.78e-31: 119: 66.04
+	Hs
		727911 ZN184_HUMAN (905-1285): 3.11e-22: 106: 11.86		SOX6_HUMAN (29-244): 2.42e-29: 120: 23.61