HitPredict

Interactor 1: RIGI (O95786)
Antiviral innate immune response receptor RIG-I (ATP-dependent RNA helicase DDX58) (EC 3.6.4.13) (DEAD box protein 58) (RIG-I-like receptor 1) (RLR-1) (RNA sensor RIG-I) (Retinoic acid-inducible gene 1 protein) (RIG-1) (Retinoic acid-inducible gene I protein) (RIG-I)
Gene: RIGI

Interactor 2: DHX36 (Q9H2U1)
ATP-dependent DNA/RNA helicase DHX36 (EC 3.6.4.12) (EC 3.6.4.13) (DEAD/H box polypeptide 36) (DEAH-box protein 36) (G4-resolvase-1) (G4R1) (MLE-like protein 1) (RNA helicase associated with AU-rich element protein)
Gene: DHX36

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 24651521
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains DEAD~DEAD, DEAD~HA2, DEAD~Helicase_C, HA2~Helicase_C, Helicase_C~Helicase_C, Helicase_C~OB_NTP_bind, DEAD~RIG-I_C, Helicase_C~RIG-I_C, DEAD~RIG-I_C-RD, Helicase_C~RIG-I_C-RD
Common GO terms GO:0002735 - positive regulation of myeloid dendritic cell cytokine production
GO:0003724 - RNA helicase activity
GO:0003725 - double-stranded RNA binding
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
and 8 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

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Last updated: 15 Jul 2024