HitPredict

Interactor 1: RIGI (O95786)
Antiviral innate immune response receptor RIG-I (ATP-dependent RNA helicase DDX58) (EC 3.6.4.13) (DEAD box protein 58) (RIG-I-like receptor 1) (RLR-1) (RNA sensor RIG-I) (Retinoic acid-inducible gene 1 protein) (RIG-1) (Retinoic acid-inducible gene I protein) (RIG-I)
Gene: RIGI

Interactor 2: CYLD (Q9NQC7)
Ubiquitin carboxyl-terminal hydrolase CYLD (EC 3.4.19.12) (Deubiquitinating enzyme CYLD) (Ubiquitin thioesterase CYLD) (Ubiquitin-specific-processing protease CYLD)
Gene: CYLD

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.612

Property	Details
Experiments	18636086, 18467330
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0008270 - zinc ion binding GO:0045087 - innate immune response
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 925 Hs			1 956
+	Hs
		1271669 DDX17_HUMAN (410-831): 1.46e-49: 189: 11.75		CYLD_HUMAN (1-956): 0: 1872: 100.00
+	Hs
		571605 DDX5_HUMAN (459-798): 1.16e-47: 182: 14.05		CYLD_HUMAN (1-956): 0: 1872: 100.00
+	Hs
		134215 DDX3X_HUMAN (411-774): 1.03e-44: 174: 13.92		CYLD_HUMAN (1-956): 0: 1872: 100.00
+	Hs
		1328090 DDX47_HUMAN (408-807): 8.54e-46: 173: 14.49		CYLD_HUMAN (1-956): 0: 1872: 100.00