HitPredict

Interactor 1: STAU1 (O95793)
Double-stranded RNA-binding protein Staufen homolog 1
Gene: STAU1

Interactor 2: M4K4 (O95819)
Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (HPK/GCK-like kinase HGK) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (Nck-interacting kinase)
Gene: MAP4K4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	30948266
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 577 Hs			1 1239
+	Hs
		322876 STAU1_HUMAN (1-577): 0: 524: 100.00		MINK1_HUMAN (1-1239): 0: 1120: 59.29
+	Hs
		322553 STAU1_HUMAN (1-577): 0: 524: 100.00		AAPK1_HUMAN (8-555): 9.95e-123: 392: 16.85
+	Hs
		322236 STAU1_HUMAN (1-577): 0: 524: 100.00		AKT1_HUMAN (2-354): 2.35e-122: 388: 20.82
+	Hs
		322560 STAU1_HUMAN (1-577): 0: 524: 100.00		STK3_HUMAN (4-499): 3.17e-119: 381: 30.60
+	Hs
		254426 STAU1_HUMAN (1-577): 0: 524: 100.00		ROCK2_HUMAN (15-536): 8.84e-107: 369: 22.02
+	Hs
		1302248 STRBP_HUMAN (48-336): 1.3e-63: 223: 17.33		MAST1_HUMAN (3-947): 3.96e-126: 426: 14.68
+	Hs
		149190 STRBP_HUMAN (48-336): 1.3e-63: 223: 17.33		CTRO_HUMAN (14-616): 3.12e-117: 405: 22.33
+	Hs
		148582 DSRAD_HUMAN (246-572): 7.91e-51: 191: 16.57		CTRO_HUMAN (14-616): 3.12e-117: 405: 22.33
+	Hs
		269943 PRKRA_HUMAN (67-353): 1.54e-30: 123: 19.42		MAST1_HUMAN (3-947): 3.96e-126: 426: 14.68
+	Hs
		148743 ILF3_HUMAN (245-488): 2.36e-15: 81.6: 15.45		CTRO_HUMAN (14-616): 3.12e-117: 405: 22.33
+	Hs
		148386 E2AK2_HUMAN (98-258): 1.74e-11: 68.9: 22.67		CTRO_HUMAN (14-616): 3.12e-117: 405: 22.33
+	Hs
		269710 PRKRA_HUMAN (67-353): 1.54e-30: 123: 19.42		M4K2_HUMAN (17-292): 1.97e-64: 237: 45.71