HitPredict

Interactor 1: STAU1 (O95793)
Double-stranded RNA-binding protein Staufen homolog 1
Gene: STAU1

Interactor 2: ERF3A (P15170)
Eukaryotic peptide chain release factor GTP-binding subunit ERF3A (Eukaryotic peptide chain release factor subunit 3a) (eRF3a) (EC 3.6.5.-) (G1 to S phase transition protein 1 homolog)
Gene: GSPT1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.656

Property	Details
Experiments	35271311, 30948266, 36232890
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 577 Hs			1 499
+	Hs
		322865 STAU1_HUMAN (1-577): 0: 524: 100.00		ERF3B_HUMAN (1-499): 0: 558: 93.79
+	Hs
		322462 STAU1_HUMAN (1-577): 0: 524: 100.00		EF1A1_HUMAN (70-498): 1.24e-175: 503: 38.29
+	Hs
		323356 STAU1_HUMAN (1-577): 0: 524: 100.00		HBS1L_HUMAN (3-496): 1.8e-164: 483: 38.11
+	Hs
		877236 DSRAD_HUMAN (246-572): 7.91e-51: 191: 16.57		EF1A1_HUMAN (70-498): 1.24e-175: 503: 38.29
+	Hs
		877247 DSRAD_HUMAN (246-572): 7.91e-51: 191: 16.57		EF1A2_HUMAN (70-498): 6.64e-174: 499: 37.16
+	Hs
		1222980 STAU2_HUMAN (177-569): 4.96e-21: 99: 16.46		ERF3B_HUMAN (1-499): 0: 558: 93.79
+	Hs
		545845 ILF3_HUMAN (245-488): 2.36e-15: 81.6: 15.45		ERF3A_HUMAN (1-499): 0: 567: 100.00
+	Hs
		932652 RED1_HUMAN (254-488): 1.1e-31: 132: 17.92		EF1A1_HUMAN (70-498): 1.24e-175: 503: 38.29
+	Xl
		568005 Q5MNU4_XENLA (113-554): 2.36e-13: 75.1: 15.45		EF1A1_XENLA (66-498): 1.55e-168: 485: 36.83