HitPredict

Interactor 1: STAU1 (O95793)
Double-stranded RNA-binding protein Staufen homolog 1
Gene: STAU1

Interactor 2: DDX5 (P17844)
Probable ATP-dependent RNA helicase DDX5 (EC 3.6.4.13) (DEAD box protein 5) (RNA helicase p68)
Gene: DDX5

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.54	1.00	0.737

Property	Details
Experiments	23125841, 29374155
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Helicase_C~dsrm
Common GO terms	GO:0003723 - RNA binding GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0016020 - membrane GO:0070062 - extracellular exosome
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 577 Hs			1 614
+	Hs
		322951 STAU1_HUMAN (1-577): 0: 524: 100.00		DDX17_HUMAN (30-612): 0: 534: 66.83
+	Hs
		133809 STAU1_HUMAN (1-577): 0: 524: 100.00		DDX3X_HUMAN (2-556): 9.8e-147: 441: 35.52
+	Hs
		571528 DGCR8_HUMAN (19-423): 7.12e-36: 145: 15.26		DDX5_HUMAN (1-614): 0: 624: 100.00
+	Hs
		571400 RED1_HUMAN (254-488): 1.1e-31: 132: 17.92		DDX5_HUMAN (1-614): 0: 624: 100.00
+	Hs
		571421 ILF3_HUMAN (245-488): 2.36e-15: 81.6: 15.45		DDX5_HUMAN (1-614): 0: 624: 100.00
+	Mm
		1119392 DGCR8_MOUSE (126-423): 2.47e-35: 143: 16.77		DDX17_MOUSE (30-612): 0: 536: 66.67
+	Hs
		1264621 DGCR8_HUMAN (19-423): 7.12e-36: 145: 15.26		DDX17_HUMAN (30-612): 0: 534: 66.83
+	Hs
		1019858 ILF3_HUMAN (245-488): 2.36e-15: 81.6: 15.45		DDX17_HUMAN (30-612): 0: 534: 66.83
+	Hs
		181692 RED1_HUMAN (254-488): 1.1e-31: 132: 17.92		DDX3Y_HUMAN (2-556): 1.95e-145: 438: 34.93
+	Hs
		134005 ILF3_HUMAN (245-488): 2.36e-15: 81.6: 15.45		DDX3X_HUMAN (2-556): 9.8e-147: 441: 35.52
+	Hs
		944841 RED1_HUMAN (254-488): 1.1e-31: 132: 17.92		DDX46_HUMAN (50-477): 3.83e-108: 350: 40.68