HitPredict

Interactor 1: STAU1 (O95793)
Double-stranded RNA-binding protein Staufen homolog 1
Gene: STAU1

Interactor 2: SRSF6 (Q13247)
Serine/arginine-rich splicing factor 6 (Pre-mRNA-splicing factor SRP55) (Splicing factor, arginine/serine-rich 6)
Gene: SRSF6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	30948266, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 577 Hs			1 344
+	Hs
		322520 STAU1_HUMAN (1-577): 0: 524: 100.00		SRSF1_HUMAN (3-188): 3.02e-54: 180: 36.65
+	Hs
		323083 STAU1_HUMAN (1-577): 0: 524: 100.00		RBM4_HUMAN (1-343): 1.17e-47: 166: 17.05
+	Hs
		322522 STAU1_HUMAN (1-577): 0: 524: 100.00		SRSF4_HUMAN (1-323): 1.85e-45: 163: 63.47
+	Hs
		322563 STAU1_HUMAN (1-577): 0: 524: 100.00		SRSF5_HUMAN (2-180): 3.02e-46: 160: 64.25
+	Hs
		323055 STAU1_HUMAN (1-577): 0: 524: 100.00		RBM4B_HUMAN (1-343): 2.62e-45: 160: 18.23
+	Hs
		322569 STAU1_HUMAN (1-577): 0: 524: 100.00		PABP4_HUMAN (101-191): 1.26e-12: 70.7: 21.88
+	Hs
		323216 STAU1_HUMAN (1-577): 0: 524: 100.00		RBM28_HUMAN (4-248): 1.53e-12: 70.6: 14.61
+	Hs
		322122 STAU1_HUMAN (1-577): 0: 524: 100.00		PABP1_HUMAN (101-191): 1.28e-11: 67.6: 19.79
+	Hs
		322484 STAU1_HUMAN (1-577): 0: 524: 100.00		SRSF3_HUMAN (3-78): 2.4e-09: 57.4: 46.84
+	Hs
		944753 RED1_HUMAN (254-488): 1.1e-31: 132: 17.92		SRSF1_HUMAN (3-188): 3.02e-54: 180: 36.65
+	Hs
		269707 PRKRA_HUMAN (67-353): 1.54e-30: 123: 19.42		SRSF1_HUMAN (3-188): 3.02e-54: 180: 36.65
+	Hs
		1029022 DGCR8_HUMAN (19-423): 7.12e-36: 145: 15.26		SRSF6_HUMAN (1-323): 3.2e-43: 154: 100.00
+	Hs
		944765 RED1_HUMAN (254-488): 1.1e-31: 132: 17.92		SRSF5_HUMAN (2-180): 3.02e-46: 160: 64.25
+	Hs
		269716 PRKRA_HUMAN (67-353): 1.54e-30: 123: 19.42		SRSF5_HUMAN (2-180): 3.02e-46: 160: 64.25
+	Hs
		474032 DGCR8_HUMAN (19-423): 7.12e-36: 145: 15.26		PAB4L_HUMAN (1-196): 1.97e-35: 134: 15.94
+	Hs
		269717 PRKRA_HUMAN (67-353): 1.54e-30: 123: 19.42		SRSF6_HUMAN (1-323): 3.2e-43: 154: 100.00
+	Hs
		1264673 DGCR8_HUMAN (19-423): 7.12e-36: 145: 15.26		RBM28_HUMAN (4-248): 1.53e-12: 70.6: 14.61
+	Hs
		944766 RED1_HUMAN (254-488): 1.1e-31: 132: 17.92		PABP4_HUMAN (101-191): 1.26e-12: 70.7: 21.88
+	Hs
		944965 RED1_HUMAN (254-488): 1.1e-31: 132: 17.92		RBM28_HUMAN (4-248): 1.53e-12: 70.6: 14.61
+	Hs
		269696 PRKRA_HUMAN (67-353): 1.54e-30: 123: 19.42		SRSF3_HUMAN (3-78): 2.4e-09: 57.4: 46.84