HitPredict

Interactor 1: STAU1 (O95793)
Double-stranded RNA-binding protein Staufen homolog 1
Gene: STAU1

Interactor 2: DICER (Q9UPY3)
Endoribonuclease Dicer (EC 3.1.26.3) (Helicase with RNase motif) (Helicase MOI)
Gene: DICER1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	1.00	0.827

Property	Details
Experiments	30948266, 29395067, 36232890
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Helicase_C~dsrm, Ribonuclease_3~dsrm
Common GO terms	GO:0003723 - RNA binding GO:0003725 - double-stranded RNA binding GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 577 Hs			1 1922
+	Hs
		1302246 STRBP_HUMAN (48-336): 1.3e-63: 223: 17.33		DICER_HUMAN (1-1922): 0: 1763: 100.00
+	Hs
		877391 DSRAD_HUMAN (246-572): 7.91e-51: 191: 16.57		DICER_HUMAN (1-1922): 0: 1763: 100.00
+	Hs
		322980 STAU1_HUMAN (1-577): 0: 524: 100.00		DHX58_HUMAN (43-638): 2.57e-80: 282: 21.70
+	Hs
		322157 STAU1_HUMAN (1-577): 0: 524: 100.00		DDX5_HUMAN (6-364): 3.03e-66: 239: 11.54
+	Hs
		322273 STAU1_HUMAN (1-577): 0: 524: 100.00		IF4A3_HUMAN (6-251): 1.27e-52: 193: 11.37
+	Hs
		322901 STAU1_HUMAN (1-577): 0: 524: 100.00		DDX55_HUMAN (14-339): 3.13e-47: 182: 8.67
+	Hs
		322873 STAU1_HUMAN (1-577): 0: 524: 100.00		ASCC3_HUMAN (13-493): 5.92e-31: 136: 11.18
+	Hs
		271998 STAU1_HUMAN (1-577): 0: 524: 100.00		U520_HUMAN (4-505): 1.16e-29: 132: 10.93
+	At
		1108230 DCL1_ARATH (185-353): 2.77e-36: 147: 21.02		DCL2_ARATH (1424-1913): 3.21e-96: 345: 24.47
+	Hs
		269869 PRKRA_HUMAN (67-353): 1.54e-30: 123: 19.42		IFIH1_HUMAN (33-641): 7.5e-85: 304: 19.44
+	Hs
		269593 PRKRA_HUMAN (67-353): 1.54e-30: 123: 19.42		RIGI_HUMAN (34-641): 5.74e-79: 284: 19.97
+	Hs
		571528 DGCR8_HUMAN (19-423): 7.12e-36: 145: 15.26		DDX5_HUMAN (6-364): 3.03e-66: 239: 11.54
+	Hs
		571400 RED1_HUMAN (254-488): 1.1e-31: 132: 17.92		DDX5_HUMAN (6-364): 3.03e-66: 239: 11.54
+	Dm
		1363205 LOQS_DROME (119-559): 5.84e-75: 247: 21.38		DCR1_DROME (1582-1767): 1.61e-11: 72.3: 20.41
+	Hs
		944863 RED1_HUMAN (254-488): 1.1e-31: 132: 17.92		DDX55_HUMAN (14-339): 3.13e-47: 182: 8.67
+	Hs
		269805 PRKRA_HUMAN (67-353): 1.54e-30: 123: 19.42		DDX55_HUMAN (14-339): 3.13e-47: 182: 8.67
+	Dm
		1181378 Q9V9V7_DROME (14-354): 1.16e-57: 206: 16.53		Q7KNF1_DROME (1664-1862): 5.55e-12: 73.5: 19.53
+	Hs
		877372 DSRAD_HUMAN (246-572): 7.91e-51: 191: 16.57		RNC_HUMAN (1311-1374): 1.17e-12: 75.8: 32.81
+	At
		1352640 DCL1_ARATH (185-353): 2.77e-36: 147: 21.02		DCL1_ARATH (1668-1850): 6.62e-19: 96.6: 19.51
+	Hs
		1264668 DGCR8_HUMAN (19-423): 7.12e-36: 145: 15.26		RNC_HUMAN (1311-1374): 1.17e-12: 75.8: 32.81