HitPredict

Interactor 1: TTC4 (O95801)
Tetratricopeptide repeat protein 4 (TPR repeat protein 4)
Gene: TTC4

Interactor 2: GRK6 (P43250)
G protein-coupled receptor kinase 6 (EC 2.7.11.16) (G protein-coupled receptor kinase GRK6)
Gene: GRK6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	32707033
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 387 Hs			1 576
+	Hs
		794380 FKBP5_HUMAN (10-255): 2.21e-42: 155: 17.56		GRK6_HUMAN (1-576): 0: 573: 100.00
+	Hs
		794369 PPP5_HUMAN (63-268): 4.43e-41: 153: 16.99		GRK6_HUMAN (1-576): 0: 573: 100.00
+	Hs
		981051 FKBP5_HUMAN (10-255): 2.21e-42: 155: 17.56		KPCT_HUMAN (9-508): 8.49e-153: 456: 24.32
+	Mm
		1141234 PPP5_MOUSE (63-268): 6.6e-41: 152: 16.51		ARBK1_MOUSE (2-541): 5.56e-147: 441: 36.41
+	Hs
		1035058 FKBP5_HUMAN (10-255): 2.21e-42: 155: 17.56		AKT3_HUMAN (75-496): 8.41e-145: 428: 30.97
+	Hs
		865097 TTC3_HUMAN (45-340): 1.67e-40: 155: 14.90		AKT3_HUMAN (75-496): 8.41e-145: 428: 30.97
+	Hs
		681754 TTC3_HUMAN (45-340): 1.67e-40: 155: 14.90		AKT1_HUMAN (75-497): 3.54e-143: 424: 30.59
+	Hs
		681830 FKBP5_HUMAN (10-255): 2.21e-42: 155: 17.56		AKT1_HUMAN (75-497): 3.54e-143: 424: 30.59
+	Hs
		682153 TTC3_HUMAN (45-340): 1.67e-40: 155: 14.90		AKT2_HUMAN (75-496): 7.73e-143: 423: 30.82
+	Hs
		682173 FKBP5_HUMAN (10-255): 2.21e-42: 155: 17.56		AKT2_HUMAN (75-496): 7.73e-143: 423: 30.82
+	Mm
		103653 G5E8T2_MOUSE (45-340): 4.61e-39: 150: 13.91		AKT1_MOUSE (75-497): 2.96e-144: 427: 30.59
+	Hs
		568651 FKBP5_HUMAN (10-255): 2.21e-42: 155: 17.56		KAPCA_HUMAN (144-500): 5.83e-144: 421: 28.85
+	Rn
		858690 PPP5_RAT (63-268): 7.3e-41: 152: 16.51		AKT3_RAT (75-496): 6.79e-143: 423: 30.73
+	Hs
		610723 FKBP5_HUMAN (10-255): 2.21e-42: 155: 17.56		KAPCB_HUMAN (144-500): 4.26e-143: 419: 29.69
+	Hs
		609666 FKBP5_HUMAN (10-255): 2.21e-42: 155: 17.56		KAPCG_HUMAN (144-500): 1.69e-142: 417: 26.89
+	Hs
		609656 PPP5_HUMAN (63-268): 4.43e-41: 153: 16.99		KAPCG_HUMAN (144-500): 1.69e-142: 417: 26.89
+	Mm
		682131 CHIP_MOUSE (55-365): 2.66e-39: 143: 15.24		AKT1_MOUSE (75-497): 2.96e-144: 427: 30.59
+	Hs
		568829 CHIP_HUMAN (74-365): 9.58e-39: 142: 15.88		KAPCA_HUMAN (144-500): 5.83e-144: 421: 28.85
+	Sc
		412701 CNS1_YEAST (23-358): 5e-41: 150: 22.06		KAPA_YEAST (149-502): 3.8e-127: 380: 31.11
+	Hs
		1035034 FKBP5_HUMAN (10-255): 2.21e-42: 155: 17.56		KS6B2_HUMAN (186-485): 2.72e-57: 201: 39.09