HitPredict

Interactor 1: BAG2 (O95816)
BAG family molecular chaperone regulator 2 (BAG-2) (Bcl-2-associated athanogene 2)
Gene: BAG2

Interactor 2: LRRK2 (Q5S007)
Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (EC 3.6.5.-) (Dardarin)
Gene: LRRK2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.629

Property	Details
Experiments	24510904, 29513927
Identification Methods	pull down, protein array
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0030424 - axon GO:0030425 - dendrite GO:0032091 - negative regulation of protein binding GO:0044325 - transmembrane transporter binding
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 211 Hs			1 2527
+	Hs
		72074 B3KM36_HUMAN (1-211): 5.13e-99: 287: 99.53		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		323798 BAG2_HUMAN (1-211): 3e-99: 288: 100.00		LRRK1_HUMAN (771-1194): 2.3e-35: 151: 16.38
+	Hs
		324140 BAG2_HUMAN (1-211): 3e-99: 288: 100.00		MFHA1_HUMAN (838-1119): 1.5e-30: 134: 16.95
+	Hs
		201155 BAG2_HUMAN (1-211): 3e-99: 288: 100.00		M3K7_HUMAN (1869-2132): 8.36e-23: 107: 28.83