HitPredict

Interactor 1: BAG3 (O95817)
BAG family molecular chaperone regulator 3 (BAG-3) (Bcl-2-associated athanogene 3) (Bcl-2-binding protein Bis) (Docking protein CAIR-1)
Gene: BAG3

Interactor 2: 1433G (P61981)
14-3-3 protein gamma (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein gamma, N-terminally processed]
Gene: YWHAG

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.60	0.621

Property	Details
Experiments	36931259, 23824909
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 575 Hs			1 247
+	Hs
		324321 BAG3_HUMAN (1-575): 0: 809: 100.00		1433E_HUMAN (1-244): 2.02e-141: 398: 63.53
+	Hs
		324354 BAG3_HUMAN (1-575): 0: 809: 100.00		1433F_HUMAN (1-246): 2.5e-135: 382: 86.99
+	Hs
		324251 BAG3_HUMAN (1-575): 0: 809: 100.00		1433B_HUMAN (2-247): 1.91e-109: 317: 75.40
+	Hs
		324326 BAG3_HUMAN (1-575): 0: 809: 100.00		1433Z_HUMAN (2-245): 2.39e-108: 314: 74.59
+	Hs
		324238 BAG3_HUMAN (1-575): 0: 809: 100.00		1433T_HUMAN (2-245): 5.53e-105: 305: 70.33
+	Hs
		927645 BAG5_HUMAN (418-498): 3.23e-17: 86.4: 41.98		1433Z_HUMAN (2-245): 2.39e-108: 314: 74.59