HitPredict

Interactor 1: BAG3 (O95817)
BAG family molecular chaperone regulator 3 (BAG-3) (Bcl-2-associated athanogene 3) (Bcl-2-binding protein Bis) (Docking protein CAIR-1)
Gene: BAG3

Interactor 2: PDLI7 (Q9NR12)
PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma)
Gene: PDLIM7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.90	0.60	0.736

Property	Details
Experiments	28514442, 33961781, 32296183, 23824909, 25036637, unassigned1304
Identification Methods	affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation, validated two hybrid, two hybrid array, two hybrid prey pooling approach
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0001725 - stress fiber GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0030018 - Z disc
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 575 Hs			1 457
+	Hs
		324275 BAG3_HUMAN (1-575): 0: 809: 100.00		PAXI_HUMAN (185-396): 1.45e-33: 135: 21.23
+	Hs
		324214 BAG3_HUMAN (1-575): 0: 809: 100.00		ZNF3_HUMAN (79-288): 7.43e-19: 90.4: 6.45
+	Hs
		324215 BAG3_HUMAN (1-575): 0: 809: 100.00		ZSC20_HUMAN (72-278): 3e-16: 83.5: 6.22
+	Hs
		324436 BAG3_HUMAN (1-575): 0: 809: 100.00		PDLI3_HUMAN (398-453): 1.2e-11: 68: 30.36
+	Hs
		324421 BAG3_HUMAN (1-575): 0: 809: 100.00		ZYX_HUMAN (74-336): 8.74e-11: 66.1: 13.87
+	Hs
		324413 BAG3_HUMAN (1-575): 0: 809: 100.00		TRIP6_HUMAN (396-457): 6.89e-09: 59.7: 27.42
+	Hs
		1344051 BAG5_HUMAN (418-498): 3.23e-17: 86.4: 41.98		PDLI7_HUMAN (1-457): 2.02e-91: 286: 100.00