Interactor 1: BAG3 (O95817)
BAG family molecular chaperone regulator 3 (BAG-3) (Bcl-2-associated athanogene 3) (Bcl-2-binding protein Bis) (Docking protein CAIR-1)
Gene: BAG3

Interactor 2: HSPB8 (Q9UJY1)
Heat shock protein beta-8 (HspB8) (Alpha-crystallin C chain) (E2-induced gene 1 protein) (Heat shock protein family B member 8) (Protein kinase H11) (Small stress protein-like protein HSP22)
Gene: HSPB8

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 0.60 0.762

The method score is based on:

Property Details
Experiments 21516116, 28514442, 33961781, 32707033, 16189514, 26496610, 29405094, 30559338, 32296183, 32696179, 36854646, 25036637, unassigned1304
Identification Methods two hybrid, affinity chromatography technology, anti tag coimmunoprecipitation, pull down, luminescence based mammalian interactome mapping, two hybrid prey pooling approach, validated two hybrid, two hybrid array, two hybrid pooling approach
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0034620 - cellular response to unfolded protein
and 2 others

more...

Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 575
Hs

1 196
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Dm
+ Dm
+ Dm

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Last updated: 15 Jul 2024