HitPredict

Interactor 1: M4K4 (O95819)
Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (HPK/GCK-like kinase HGK) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (Nck-interacting kinase)
Gene: MAP4K4

Interactor 2: CTNA1 (P35221)
Catenin alpha-1 (Alpha E-catenin) (Cadherin-associated protein) (Renal carcinoma antigen NY-REN-13)
Gene: CTNNA1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	34079125, 37381005
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005925 - focal adhesion
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 1239 Hs			1 906
+	Hs
		716803 TNIK_HUMAN (1-1239): 0: 1101: 60.56		CTNA1_HUMAN (1-906): 0: 1080: 100.00
+	Mm
		949295 TNIK_MOUSE (1-1239): 0: 1120: 62.43		CTNA2_MOUSE (6-905): 0: 1044: 77.77
+	Hs
		647837 MARK3_HUMAN (16-665): 4.1e-127: 411: 16.23		CTNA1_HUMAN (1-906): 0: 1080: 100.00
+	Hs
		148452 CTRO_HUMAN (14-616): 3.12e-117: 405: 22.33		CTNA1_HUMAN (1-906): 0: 1080: 100.00
+	Hs
		681689 AKT1_HUMAN (2-354): 2.35e-122: 388: 20.82		CTNA1_HUMAN (1-906): 0: 1080: 100.00
+	Hs
		1299978 NEK1_HUMAN (23-917): 5.54e-125: 418: 17.52		CTNL1_HUMAN (147-847): 1.84e-63: 230: 14.83