HitPredict

Interactor 1: M4K4 (O95819)
Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (HPK/GCK-like kinase HGK) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (Nck-interacting kinase)
Gene: MAP4K4

Interactor 2: CXAR (P78310)
Coxsackievirus and adenovirus receptor (CAR) (hCAR) (CVB3-binding protein) (Coxsackievirus B-adenovirus receptor) (HCVADR)
Gene: CXADR

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Pkinase~V-set
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 1239 Hs			1 365
+	Hs
		940597 TNIK_HUMAN (1-1239): 0: 1101: 60.56		CXAR_HUMAN (1-365): 5.66e-82: 256: 100.00
+	Hs
		68219 M4K4_HUMAN (1-1239): 0: 1227: 100.00		HECA2_HUMAN (13-254): 1.21e-23: 103: 20.00
+	Hs
		647871 MARK3_HUMAN (16-665): 4.1e-127: 411: 16.23		CXAR_HUMAN (1-365): 5.66e-82: 256: 100.00
+	Hs
		940471 MARK2_HUMAN (8-669): 2.09e-122: 399: 14.10		CXAR_HUMAN (1-365): 5.66e-82: 256: 100.00
+	Hs
		940612 M4K5_HUMAN (4-375): 4.65e-107: 359: 39.52		CXAR_HUMAN (1-365): 5.66e-82: 256: 100.00
+	Hs
		149131 CTRO_HUMAN (14-616): 3.12e-117: 405: 22.33		PXDN_HUMAN (14-364): 1.29e-53: 192: 15.39