HitPredict

Interactor 1: M4K4 (O95819)
Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (HPK/GCK-like kinase HGK) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (Nck-interacting kinase)
Gene: MAP4K4

Interactor 2: AP3S1 (Q92572)
AP-3 complex subunit sigma-1 (AP-3 complex subunit sigma-3A) (Adaptor-related protein complex 3 subunit sigma-1) (Clathrin-associated/assembly/adaptor protein, small 3) (Sigma-3A-adaptin) (Sigma3A-adaptin) (Sigma-adaptin 3a)
Gene: AP3S1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	32640226
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 1239 Hs			1 193
+	Hs
		324907 M4K4_HUMAN (1-1239): 0: 1227: 100.00		AP3M1_HUMAN (1-188): 1.37e-44: 154: 18.09
+	Hs
		1233569 MINK1_HUMAN (1-1239): 0: 1120: 59.29		AP3M1_HUMAN (1-188): 1.37e-44: 154: 18.09
+	Hs
		1377252 MAST1_HUMAN (3-947): 3.96e-126: 426: 14.68		AP1M2_HUMAN (3-186): 1.66e-42: 149: 15.76
+	Hs
		149154 CTRO_HUMAN (14-616): 3.12e-117: 405: 22.33		AP2M1_HUMAN (1-186): 6.1e-47: 160: 11.83
+	Hs
		1183090 MARK2_HUMAN (8-669): 2.09e-122: 399: 14.10		AP2M1_HUMAN (1-186): 6.1e-47: 160: 11.83
+	Hs
		1018203 M4K2_HUMAN (17-292): 1.97e-64: 237: 45.71		AP3M1_HUMAN (1-188): 1.37e-44: 154: 18.09