HitPredict

Interactor 1: M4K4 (O95819)
Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (HPK/GCK-like kinase HGK) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (Nck-interacting kinase)
Gene: MAP4K4

Interactor 2: EGLN3 (Q9H6Z9)
Prolyl hydroxylase EGLN3 (EC 1.14.11.-) (Egl nine homolog 3) (EC 1.14.11.29) (HPH-1) (Hypoxia-inducible factor prolyl hydroxylase 3) (HIF-PH3) (HIF-prolyl hydroxylase 3) (HPH-3) (Prolyl hydroxylase domain-containing protein 3) (PHD3)
Gene: EGLN3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	26972000
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 1239 Hs			1 239
+	Hs
		1332798 SIK3_HUMAN (7-915): 2.5e-127: 426: 15.13		EGLN3_HUMAN (1-239): 5.66e-162: 449: 100.00
+	Hs
		1027435 STK3_HUMAN (4-499): 3.17e-119: 381: 30.60		EGLN3_HUMAN (1-239): 5.66e-162: 449: 100.00
+	Hs
		1023115 STK4_HUMAN (4-517): 8.55e-119: 379: 31.92		EGLN3_HUMAN (1-239): 5.66e-162: 449: 100.00
+	Hs
		682205 AKT2_HUMAN (2-354): 7.38e-124: 393: 21.98		EGLN1_HUMAN (2-225): 3.05e-143: 409: 64.29
+	Hs
		682020 AKT1_HUMAN (2-354): 2.35e-122: 388: 20.82		EGLN1_HUMAN (2-225): 3.05e-143: 409: 64.29