HitPredict

Interactor 1: M4K4 (O95819)
Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (HPK/GCK-like kinase HGK) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (Nck-interacting kinase)
Gene: MAP4K4

Interactor 2: FGOP2 (Q9NVK5)
FGFR1 oncogene partner 2
Gene: FGFR1OP2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.50	0.533

Property	Details
Experiments	26496610, 32640226
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 1239 Hs			1 253
+	Hs
		91411 E7EN19_HUMAN (1-1239): 0: 1171: 91.79		FGOP2_HUMAN (1-253): 2.35e-93: 276: 100.00
+	Hs
		324869 M4K4_HUMAN (1-1239): 0: 1227: 100.00		SIKE1_HUMAN (1-238): 2.85e-56: 180: 43.50
+	Hs
		1233551 MINK1_HUMAN (1-1239): 0: 1120: 59.29		FGOP2_HUMAN (1-253): 2.35e-93: 276: 100.00
+	Hs
		1346707 TNIK_HUMAN (1-1239): 0: 1101: 60.56		FGOP2_HUMAN (1-253): 2.35e-93: 276: 100.00
+	Hs
		1310716 TNIK_HUMAN (1-1239): 0: 1101: 60.56		SIKE1_HUMAN (1-238): 2.85e-56: 180: 43.50
+	Hs
		1027445 STK3_HUMAN (4-499): 3.17e-119: 381: 30.60		FGOP2_HUMAN (1-253): 2.35e-93: 276: 100.00
+	Hs
		1023126 STK4_HUMAN (4-517): 8.55e-119: 379: 31.92		FGOP2_HUMAN (1-253): 2.35e-93: 276: 100.00
+	Hs
		131613 STK25_HUMAN (14-452): 5.34e-114: 364: 34.99		FGOP2_HUMAN (1-253): 2.35e-93: 276: 100.00
+	Hs
		1346705 STK26_HUMAN (16-414): 6.13e-111: 355: 34.05		FGOP2_HUMAN (1-253): 2.35e-93: 276: 100.00
+	Hs
		1346716 STK24_HUMAN (20-398): 2.05e-110: 355: 36.65		FGOP2_HUMAN (1-253): 2.35e-93: 276: 100.00
+	Hs
		1240585 Q8NBY1_HUMAN (16-414): 1.29e-110: 354: 35.41		FGOP2_HUMAN (1-253): 2.35e-93: 276: 100.00
+	Hs
		131600 STK25_HUMAN (14-452): 5.34e-114: 364: 34.99		SIKE1_HUMAN (1-238): 2.85e-56: 180: 43.50
+	Hs
		1310712 STK26_HUMAN (16-414): 6.13e-111: 355: 34.05		SIKE1_HUMAN (1-238): 2.85e-56: 180: 43.50
+	Hs
		1310721 STK24_HUMAN (20-398): 2.05e-110: 355: 36.65		SIKE1_HUMAN (1-238): 2.85e-56: 180: 43.50
+	Dm
		1249843 HIPPO_DROME (14-316): 8.94e-108: 356: 40.79		FGOP2_DROME (4-223): 3.08e-53: 176: 27.73