HitPredict

Interactor 1: M4K4 (O95819)
Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (HPK/GCK-like kinase HGK) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (Nck-interacting kinase)
Gene: MAP4K4

Interactor 2: KCNE3 (Q9Y6H6)
Potassium voltage-gated channel subfamily E member 3 (MinK-related peptide 2) (Minimum potassium ion channel-related peptide 2) (Potassium channel subunit beta MiRP2)
Gene: KCNE3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 1239 Hs			1 103
+	Hs
		1233576 MINK1_HUMAN (1-1239): 0: 1120: 59.29		KCNE3_HUMAN (1-103): 7.78e-72: 210: 100.00
+	Hs
		1356428 TNIK_HUMAN (1-1239): 0: 1101: 60.56		KCNE3_HUMAN (1-103): 7.78e-72: 210: 100.00
+	Hs
		1296793 MARK4_HUMAN (16-693): 2.51e-123: 400: 18.06		KCNE3_HUMAN (1-103): 7.78e-72: 210: 100.00
+	Hs
		1183161 MARK2_HUMAN (8-669): 2.09e-122: 399: 14.10		KCNE3_HUMAN (1-103): 7.78e-72: 210: 100.00