Interactor 1: AIFM1 (O95831)
Apoptosis-inducing factor 1, mitochondrial (EC 1.6.99.-) (Programmed cell death protein 8)
Gene: AIFM1

Interactor 2: THIO (P10599)
Thioredoxin (Trx) (ATL-derived factor) (ADF) (Surface-associated sulphydryl protein) (SASP) (allergen Hom s Trx)
Gene: TXN

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.71 1.00 0.848

The method score is based on:

Property Details
Experiments 29568061, 33961781, unassigned1655
Identification Methods proximity labelling technology, affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Pyr_redox_2~Thioredoxin
Common GO terms GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 613
Hs

1 105
+ Hs
+ Dm
+ At
+ At
+ At

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Last updated: 15 Jul 2024