HitPredict

Interactor 1: AIFM1 (O95831)
Apoptosis-inducing factor 1, mitochondrial (EC 1.6.99.-) (Programmed cell death protein 8)
Gene: AIFM1

Interactor 2: KMCP1 (Q5SVS4)
Kidney mitochondrial carrier protein 1 (Solute carrier family 25 member 30) (Uncoupling protein 6)
Gene: SLC25A30

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005739 - mitochondrion GO:0005743 - mitochondrial inner membrane
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 613 Hs			1 291
+	Hs
		325140 AIFM1_HUMAN (1-613): 0: 581: 100.00		M2OM_HUMAN (9-288): 5.38e-49: 166: 34.84
+	Hs
		325450 AIFM1_HUMAN (1-613): 0: 581: 100.00		S2513_HUMAN (204-291): 1.65e-20: 93.3: 30.34
+	Hs
		274463 AIFM1_HUMAN (1-613): 0: 581: 100.00		S2512_HUMAN (9-109): 6.41e-20: 91.4: 26.73
+	Hs
		325229 AIFM1_HUMAN (1-613): 0: 581: 100.00		SCMC1_HUMAN (174-290): 1.83e-16: 81: 17.95
+	Hs
		325228 AIFM1_HUMAN (1-613): 0: 581: 100.00		SCMC2_HUMAN (200-290): 2.1e-15: 77.9: 21.98
+	Hs
		325363 AIFM1_HUMAN (1-613): 0: 581: 100.00		SCMC3_HUMAN (190-291): 2.44e-14: 74.8: 18.63
+	Hs
		324989 AIFM1_HUMAN (1-613): 0: 581: 100.00		ADT2_HUMAN (199-291): 1.97e-13: 71: 20.21