HitPredict

Interactor 1: AIFM1 (O95831)
Apoptosis-inducing factor 1, mitochondrial (EC 1.6.99.-) (Programmed cell death protein 8)
Gene: AIFM1

Interactor 2: KANK2 (Q63ZY3)
KN motif and ankyrin repeat domain-containing protein 2 (Ankyrin repeat domain-containing protein 25) (Matrix-remodeling-associated protein 3) (SRC-1-interacting protein) (SIP) (SRC-interacting protein) (SRC1-interacting protein)
Gene: KANK2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.67	0.60	0.635

Property	Details
Experiments	33961781, 22371500
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005739 - mitochondrion GO:0006915 - apoptotic process
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 613 Hs			1 851
+	Hs
		325394 AIFM1_HUMAN (1-613): 0: 581: 100.00		Q9H4D1_HUMAN (286-768): 4.3e-29: 126: 14.13
+	Hs
		325116 AIFM1_HUMAN (1-613): 0: 581: 100.00		RIPK4_HUMAN (246-768): 2.6e-27: 120: 13.97
+	Hs
		325328 AIFM1_HUMAN (1-613): 0: 581: 100.00		EHMT2_HUMAN (5-742): 2.01e-21: 102: 10.40
+	Hs
		276133 DLDH_HUMAN (108-599): 3.31e-98: 310: 14.59		PSD10_HUMAN (675-851): 2.07e-47: 170: 21.47