HitPredict

Interactor 1: AIFM1 (O95831)
Apoptosis-inducing factor 1, mitochondrial (EC 1.6.99.-) (Programmed cell death protein 8)
Gene: AIFM1

Interactor 2: TBA1A (Q71U36)
Tubulin alpha-1A chain (EC 3.6.5.-) (Alpha-tubulin 3) (Tubulin B-alpha-1) (Tubulin alpha-3 chain) [Cleaved into: Detyrosinated tubulin alpha-1A chain]
Gene: TUBA1A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	33961781, 27291054
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0051402 - neuron apoptotic process GO:1902065 - response to L-glutamate
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 613 Hs			1 451
+	Hs
		325351 AIFM1_HUMAN (1-613): 0: 581: 100.00		TBA1C_HUMAN (1-451): 0: 726: 98.00
+	Hs
		325128 AIFM1_HUMAN (1-613): 0: 581: 100.00		TBA4A_HUMAN (1-450): 0: 717: 96.00
+	Hs
		325235 AIFM1_HUMAN (1-613): 0: 581: 100.00		TBA3E_HUMAN (1-440): 0: 698: 97.05
+	Hs
		324993 AIFM1_HUMAN (1-613): 0: 581: 100.00		TBB5_HUMAN (1-439): 0: 695: 40.77
+	Hs
		325129 AIFM1_HUMAN (1-613): 0: 581: 100.00		TBB4B_HUMAN (1-437): 0: 693: 40.50
+	Hs
		1130103 Q5RZ99_HUMAN (112-336): 4.7e-68: 222: 98.67		TBA3E_HUMAN (1-440): 0: 698: 97.05