HitPredict

Interactor 1: LATS1 (O95835)
Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) (WARTS protein kinase) (h-warts)
Gene: LATS1

Interactor 2: K1C16 (P08779)
Keratin, type I cytoskeletal 16 (Cytokeratin-16) (CK-16) (Keratin-16) (K16)
Gene: KRT16

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35941108
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0030216 - keratinocyte differentiation
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 1130 Hs			1 473
+	Hs
		325740 LATS1_HUMAN (1-1130): 0: 934: 100.00		K1H1_HUMAN (67-443): 1.23e-142: 416: 51.72
+	Hs
		325699 LATS1_HUMAN (1-1130): 0: 934: 100.00		K1C17_HUMAN (62-464): 3.17e-139: 408: 69.31
+	Hs
		325794 LATS1_HUMAN (1-1130): 0: 934: 100.00		K2C73_HUMAN (5-431): 1.11e-94: 298: 24.94
+	Hs
		325658 LATS1_HUMAN (1-1130): 0: 934: 100.00		K2C6C_HUMAN (27-447): 3.26e-75: 248: 25.06
+	Hs
		325613 LATS1_HUMAN (1-1130): 0: 934: 100.00		K2C5_HUMAN (82-431): 2.58e-74: 246: 26.14
+	Hs
		325582 LATS1_HUMAN (1-1130): 0: 934: 100.00		K2C6A_HUMAN (27-447): 3.16e-74: 245: 25.06
+	Hs
		1071451 ST38L_HUMAN (627-1089): 2.37e-167: 503: 40.82		K1H1_HUMAN (67-443): 1.23e-142: 416: 51.72
+	Hs
		531325 AKT1_HUMAN (595-1081): 5.84e-141: 435: 24.50		K1C10_HUMAN (112-422): 7.57e-130: 390: 67.52
+	Hs
		1055200 AKT3_HUMAN (603-1081): 5.7e-143: 440: 24.54		K1H2_HUMAN (38-437): 1.86e-79: 255: 48.00
+	Hs
		681844 AKT1_HUMAN (595-1081): 5.84e-141: 435: 24.50		K1H2_HUMAN (38-437): 1.86e-79: 255: 48.00
+	Hs
		1071229 Q6PJG3_HUMAN (1-117): 2.14e-61: 207: 99.15		K1H1_HUMAN (67-443): 1.23e-142: 416: 51.72