HitPredict

Interactor 1: LATS1 (O95835)
Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) (WARTS protein kinase) (h-warts)
Gene: LATS1

Interactor 2: CAV1 (Q03135)
Caveolin-1
Gene: CAV1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.52	0.60	0.563

Property	Details
Experiments	24107629, 34079125
Identification Methods	unspecified method, proximity labelling technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0019901 - protein kinase binding GO:0033138 - positive regulation of peptidyl-serine phosphorylation GO:0090090 - negative regulation of canonical Wnt signaling pathway
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 1130 Hs			1 178
+	Hs
		974828 STK38_HUMAN (622-1089): 5.96e-165: 497: 40.17		CAV1_HUMAN (1-178): 2.82e-109: 310: 100.00
+	Hs
		568632 KAPCA_HUMAN (661-1058): 6.14e-138: 422: 31.59		CAV1_HUMAN (1-178): 2.82e-109: 310: 100.00
+	Hs
		848546 STK38_HUMAN (622-1089): 5.96e-165: 497: 40.17		CAV2_HUMAN (53-177): 5.1e-59: 183: 40.80
+	Hs
		974864 MRCKA_HUMAN (694-1047): 2.92e-66: 248: 39.06		CAV1_HUMAN (1-178): 2.82e-109: 310: 100.00