HitPredict

Interactor 1: LATS1 (O95835)
Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) (WARTS protein kinase) (h-warts)
Gene: LATS1

Interactor 2: GOGA2 (Q08379)
Golgin subfamily A member 2 (130 kDa cis-Golgi matrix protein) (GM130) (GM130 autoantigen) (Golgin-95)
Gene: GOLGA2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	25416956
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000922 - spindle pole GO:0019901 - protein kinase binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1130 Hs			1 1002
+	Hs
		325608 LATS1_HUMAN (1-1130): 0: 934: 100.00		MYH1_HUMAN (424-973): 4.56e-21: 102: 12.34
+	Hs
		325611 LATS1_HUMAN (1-1130): 0: 934: 100.00		MYH6_HUMAN (495-1001): 1.29e-20: 100: 12.23
+	Hs
		325955 LATS1_HUMAN (1-1130): 0: 934: 100.00		MYH4_HUMAN (421-973): 1.1e-20: 100: 12.27
+	Hs
		325609 LATS1_HUMAN (1-1130): 0: 934: 100.00		MYH7_HUMAN (489-981): 2.76e-18: 93.2: 13.40
+	Hs
		325935 LATS1_HUMAN (1-1130): 0: 934: 100.00		MYH2_HUMAN (513-993): 2.16e-18: 93.2: 12.89
+	Hs
		325612 LATS1_HUMAN (1-1130): 0: 934: 100.00		MYH8_HUMAN (489-981): 5.04e-18: 92.1: 13.00
+	Hs
		325605 LATS1_HUMAN (1-1130): 0: 934: 100.00		MYH3_HUMAN (548-1001): 7e-16: 85.2: 11.06
+	Hs
		325936 LATS1_HUMAN (1-1130): 0: 934: 100.00		MYH13_HUMAN (541-1001): 4.4e-15: 82.5: 10.78
+	Hs
		325919 LATS1_HUMAN (1-1130): 0: 934: 100.00		DAPLE_HUMAN (329-961): 1.5e-14: 80.7: 13.08
+	Hs
		325758 LATS1_HUMAN (1-1130): 0: 934: 100.00		GRDN_HUMAN (407-1001): 1.78e-12: 74: 10.63
+	Hs
		1344953 LATS2_HUMAN (13-1121): 0: 751: 49.61		DAPLE_HUMAN (329-961): 1.5e-14: 80.7: 13.08
+	Hs
		725079 ST38L_HUMAN (627-1089): 2.37e-167: 503: 40.82		MYH9_HUMAN (12-375): 3.45e-11: 69.7: 9.87
+	Hs
		568568 KAPCA_HUMAN (661-1058): 6.14e-138: 422: 31.59		MYH10_HUMAN (449-991): 1.35e-23: 110: 9.74
+	Hs
		522538 KAPCB_HUMAN (661-1055): 5.19e-133: 410: 31.58		MYH1_HUMAN (424-973): 4.56e-21: 102: 12.34
+	Hs
		528359 KAPCB_HUMAN (661-1055): 5.19e-133: 410: 31.58		MYH6_HUMAN (495-1001): 1.29e-20: 100: 12.23
+	Hs
		681881 AKT1_HUMAN (595-1081): 5.84e-141: 435: 24.50		GRDN_HUMAN (407-1001): 1.78e-12: 74: 10.63
+	Hs
		681696 AKT1_HUMAN (595-1081): 5.84e-141: 435: 24.50		MYH9_HUMAN (12-375): 3.45e-11: 69.7: 9.87
+	Hs
		610795 KAPCB_HUMAN (661-1055): 5.19e-133: 410: 31.58		MYH2_HUMAN (513-993): 2.16e-18: 93.2: 12.89
+	Hs
		568689 KAPCA_HUMAN (661-1058): 6.14e-138: 422: 31.59		GRDN_HUMAN (407-1001): 1.78e-12: 74: 10.63
+	Hs
		568567 KAPCA_HUMAN (661-1058): 6.14e-138: 422: 31.59		MYH9_HUMAN (12-375): 3.45e-11: 69.7: 9.87