HitPredict

Interactor 1: LATS1 (O95835)
Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) (WARTS protein kinase) (h-warts)
Gene: LATS1

Interactor 2: TRAF1 (Q13077)
TNF receptor-associated factor 1 (Epstein-Barr virus-induced protein 6)
Gene: TRAF1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.57	0.60	0.586

Property	Details
Experiments	25416956, 35941108
Identification Methods	two hybrid, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 1130 Hs			1 416
+	Hs
		325710 LATS1_HUMAN (1-1130): 0: 934: 100.00		TRAF2_HUMAN (3-415): 4e-124: 370: 38.01
+	Hs
		682088 AKT1_HUMAN (595-1081): 5.84e-141: 435: 24.50		TRAF6_HUMAN (15-414): 1.57e-103: 318: 22.98
+	Mm
		682105 AKT1_MOUSE (595-1081): 6.22e-141: 435: 24.50		TRAF6_MOUSE (15-414): 1.94e-101: 313: 22.51
+	Hs
		610801 KAPCB_HUMAN (661-1055): 5.19e-133: 410: 31.58		TRAF6_HUMAN (15-414): 1.57e-103: 318: 22.98
+	Hs
		1023698 Q6PJG3_HUMAN (1-117): 2.14e-61: 207: 99.15		TRAF1_HUMAN (1-416): 4.57e-172: 489: 100.00
+	Hs
		1024679 STK38_HUMAN (622-1089): 5.96e-165: 497: 40.17		TRAF3_HUMAN (3-262): 9.64e-11: 65.3: 15.77
+	Mm
		1141432 STK38_MOUSE (622-1089): 1.88e-162: 491: 39.74		TRAF3_MOUSE (1-262): 2.34e-12: 70.7: 16.37
+	Hs
		682006 AKT1_HUMAN (595-1081): 5.84e-141: 435: 24.50		TRAF4_HUMAN (27-136): 3.55e-09: 60.3: 17.86
+	Hs
		610720 KAPCB_HUMAN (661-1055): 5.19e-133: 410: 31.58		TRAF3_HUMAN (3-262): 9.64e-11: 65.3: 15.77