HitPredict

Interactor 1: LATS1 (O95835)
Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) (WARTS protein kinase) (h-warts)
Gene: LATS1

Interactor 2: CE350 (Q5VT06)
Centrosome-associated protein 350 (Cep350) (Centrosome-associated protein of 350 kDa)
Gene: CEP350

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005813 - centrosome
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 1130 Hs			1 3117
+	Hs
		317194 LATS1_HUMAN (1-1130): 0: 934: 100.00		PCNT_HUMAN (1316-2932): 1.6e-35: 152: 12.02
+	Hs
		325737 LATS1_HUMAN (1-1130): 0: 934: 100.00		PLEC_HUMAN (1444-2943): 4.71e-31: 137: 11.26
+	Hs
		325611 LATS1_HUMAN (1-1130): 0: 934: 100.00		MYH6_HUMAN (1192-2191): 2.45e-24: 115: 11.71
+	Hs
		325609 LATS1_HUMAN (1-1130): 0: 934: 100.00		MYH7_HUMAN (1200-2178): 5.82e-24: 114: 10.99
+	Hs
		325955 LATS1_HUMAN (1-1130): 0: 934: 100.00		MYH4_HUMAN (1166-2189): 1.63e-21: 105: 9.52
+	Hs
		325936 LATS1_HUMAN (1-1130): 0: 934: 100.00		MYH13_HUMAN (2131-2962): 1.07e-16: 90.2: 11.41
+	Hs
		325608 LATS1_HUMAN (1-1130): 0: 934: 100.00		MYH1_HUMAN (2117-2938): 4.66e-15: 84.4: 11.56
+	Hs
		317209 KAPCA_HUMAN (661-1058): 6.14e-138: 422: 31.59		PCNT_HUMAN (1316-2932): 1.6e-35: 152: 12.02
+	Hs
		681865 AKT1_HUMAN (595-1081): 5.84e-141: 435: 24.50		TBCE_HUMAN (2499-2885): 5.88e-31: 132: 15.70
+	Hs
		681975 AKT1_HUMAN (595-1081): 5.84e-141: 435: 24.50		CLIP3_HUMAN (2374-2648): 4.81e-28: 124: 23.13
+	Hs
		682199 AKT2_HUMAN (603-1075): 3.93e-140: 433: 25.31		CLIP3_HUMAN (2374-2648): 4.81e-28: 124: 23.13
+	Mm
		82707 AKT1_MOUSE (595-1081): 6.22e-141: 435: 24.50		CLIP3_MOUSE (2399-2648): 1.47e-26: 119: 22.40
+	Mm
		82708 AKT2_MOUSE (603-1081): 2.58e-139: 431: 25.81		CLIP3_MOUSE (2399-2648): 1.47e-26: 119: 22.40
+	Hs
		528359 KAPCB_HUMAN (661-1055): 5.19e-133: 410: 31.58		MYH6_HUMAN (1192-2191): 2.45e-24: 115: 11.71
+	Hs
		610802 KAPCB_HUMAN (661-1055): 5.19e-133: 410: 31.58		MYH4_HUMAN (1166-2189): 1.63e-21: 105: 9.52
+	Hs
		681840 AKT1_HUMAN (595-1081): 5.84e-141: 435: 24.50		DCTN1_HUMAN (1488-1912): 4.86e-10: 68: 18.49
+	Hs
		522538 KAPCB_HUMAN (661-1055): 5.19e-133: 410: 31.58		MYH1_HUMAN (2117-2938): 4.66e-15: 84.4: 11.56
+	Rn
		222476 MRCKA_RAT (694-1047): 1.29e-65: 245: 38.78		MRCKB_RAT (1347-1918): 1.06e-32: 142: 15.71
+	Rn
		1186812 MRCKB_RAT (695-1047): 2.19e-62: 235: 38.06		MRCKB_RAT (1347-1918): 1.06e-32: 142: 15.71