HitPredict

Interactor 1: LATS1 (O95835)
Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) (WARTS protein kinase) (h-warts)
Gene: LATS1

Interactor 2: CENPJ (Q9HC77)
Centromere protein J (CENP-J) (Centrosomal P4.1-associated protein) (LAG-3-associated protein) (LYST-interacting protein 1)
Gene: CENPJ

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005813 - centrosome GO:0005829 - cytosol GO:0019901 - protein kinase binding GO:0051301 - cell division
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1130 Hs			1 1338
+	Hs
		1335843 LATS2_HUMAN (13-1121): 0: 751: 49.61		CENPJ_HUMAN (1-1338): 7.36e-158: 512: 100.00
+	Hs
		325612 LATS1_HUMAN (1-1130): 0: 934: 100.00		MYH8_HUMAN (356-1218): 4.54e-31: 135: 8.98
+	Hs
		325611 LATS1_HUMAN (1-1130): 0: 934: 100.00		MYH6_HUMAN (356-1181): 9.56e-31: 134: 10.32
+	Hs
		325936 LATS1_HUMAN (1-1130): 0: 934: 100.00		MYH13_HUMAN (348-1209): 8e-29: 128: 8.34
+	Hs
		325935 LATS1_HUMAN (1-1130): 0: 934: 100.00		MYH2_HUMAN (70-963): 5.61e-28: 125: 9.92
+	Hs
		325608 LATS1_HUMAN (1-1130): 0: 934: 100.00		MYH1_HUMAN (70-935): 1.94e-27: 123: 7.84
+	Hs
		325955 LATS1_HUMAN (1-1130): 0: 934: 100.00		MYH4_HUMAN (70-935): 6.8e-27: 122: 7.61
+	Hs
		325609 LATS1_HUMAN (1-1130): 0: 934: 100.00		MYH7_HUMAN (431-1261): 4.84e-26: 119: 8.67
+	Hs
		325605 LATS1_HUMAN (1-1130): 0: 934: 100.00		MYH3_HUMAN (70-954): 9.99e-25: 114: 9.12
+	Hs
		725079 ST38L_HUMAN (627-1089): 2.37e-167: 503: 40.82		MYH9_HUMAN (706-1191): 3.3e-14: 80.5: 10.51
+	Dm
		1213452 WARTS_DROME (161-1065): 1.96e-152: 486: 39.48		Q8INC3_DROME (119-791): 4.39e-15: 83.2: 10.62
+	Dm
		1001877 WARTS_DROME (161-1065): 1.96e-152: 486: 39.48		Q0KI67_DROME (119-791): 1.92e-14: 81.3: 10.62
+	Hs
		528359 KAPCB_HUMAN (661-1055): 5.19e-133: 410: 31.58		MYH6_HUMAN (356-1181): 9.56e-31: 134: 10.32
+	Hs
		568568 KAPCA_HUMAN (661-1058): 6.14e-138: 422: 31.59		MYH10_HUMAN (401-1280): 4.97e-27: 122: 9.17
+	Hs
		610795 KAPCB_HUMAN (661-1055): 5.19e-133: 410: 31.58		MYH2_HUMAN (70-963): 5.61e-28: 125: 9.92
+	Hs
		522538 KAPCB_HUMAN (661-1055): 5.19e-133: 410: 31.58		MYH1_HUMAN (70-935): 1.94e-27: 123: 7.84
+	Hs
		610802 KAPCB_HUMAN (661-1055): 5.19e-133: 410: 31.58		MYH4_HUMAN (70-935): 6.8e-27: 122: 7.61
+	Hs
		681696 AKT1_HUMAN (595-1081): 5.84e-141: 435: 24.50		MYH9_HUMAN (706-1191): 3.3e-14: 80.5: 10.51
+	Hs
		568567 KAPCA_HUMAN (661-1058): 6.14e-138: 422: 31.59		MYH9_HUMAN (706-1191): 3.3e-14: 80.5: 10.51
+	Hs
		551616 AKT1_HUMAN (595-1081): 5.84e-141: 435: 24.50		DESP_HUMAN (653-1103): 3.01e-09: 64.2: 15.30